Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients
Objective:This epidemiological study was conducted in the joint haematology-orthopaedics clinic of a university hospital. The aim was to analyse the data in terms of age and radiology of patients with moderate or severe haemophilia A and knee involvement. Materials and Method:This was a retrospectiv...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sakarya University
2019-09-01
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| Series: | Sakarya Tıp Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/807357 |
| _version_ | 1827377861483298816 |
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| author | Levent Bayam Justine Theaker Sanat V Shah |
| author_facet | Levent Bayam Justine Theaker Sanat V Shah |
| author_sort | Levent Bayam |
| collection | DOAJ |
| description | Objective:This epidemiological
study was conducted in the
joint haematology-orthopaedics
clinic of a university hospital. The aim was to analyse the
data in terms of age and radiology of
patients with moderate
or severe haemophilia A and knee involvement. Materials and Method:This was a retrospective study
49 patients with knee problems out of 130 haemophilia A and
musculoskeletal problems.
Kellgren-Lawrence (KL) classification was used for
radiological assessments of osteoarthritis degree. Results:KL degree was 3 or 4 for most patients (27/39,
69.23%) in the group. There was statistically a meaningful correlation between
KL degree and patients’ age (Spearman’s: rs
= 0.512, p = 0.001). There were 7 patients with KL degree
4 at the age of 50 or younger (14.29%). 25 patients in 49(51.02%)
had total knee arthroplasty(TKA) and 10(40%) of those was bilateral. Mean age for bilateral
TKA(56.35) was
higher than unilateral(49.87). There was a statistically meaningful
correlation between patient age and the patients with
TKA (Spearman’s: rs
= 0.338, p = 0.017).
There were 2 revision surgeries out of 35 TKA (5.71%).
Most of the patients had prophylactic factor treatment (43,
87.75%). Conclusion:
Our study signify the high ratio of bilateral
knee replacements in haemophilia A patients and how early age they progressed
to KL stage 4 comparing to normal population. These results show the importance
of patient care in this group of patients, close follow-up and prophylactic
treatment. They should be managed in experienced centres by an experience team
to decrease the risks and complications. |
| first_indexed | 2024-03-08T12:45:24Z |
| format | Article |
| id | doaj.art-73431129da2b4459afbfbda94f70f74c |
| institution | Directory Open Access Journal |
| issn | 2146-409X |
| language | English |
| last_indexed | 2024-03-08T12:45:24Z |
| publishDate | 2019-09-01 |
| publisher | Sakarya University |
| record_format | Article |
| series | Sakarya Tıp Dergisi |
| spelling | doaj.art-73431129da2b4459afbfbda94f70f74c2024-01-21T07:40:06ZengSakarya UniversitySakarya Tıp Dergisi2146-409X2019-09-019350651210.31832/smj.57307428Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A PatientsLevent Bayam0Justine Theaker1Sanat V Shah2SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİManchester University HospitalsManchester University HospitalsObjective:This epidemiological study was conducted in the joint haematology-orthopaedics clinic of a university hospital. The aim was to analyse the data in terms of age and radiology of patients with moderate or severe haemophilia A and knee involvement. Materials and Method:This was a retrospective study 49 patients with knee problems out of 130 haemophilia A and musculoskeletal problems. Kellgren-Lawrence (KL) classification was used for radiological assessments of osteoarthritis degree. Results:KL degree was 3 or 4 for most patients (27/39, 69.23%) in the group. There was statistically a meaningful correlation between KL degree and patients’ age (Spearman’s: rs = 0.512, p = 0.001). There were 7 patients with KL degree 4 at the age of 50 or younger (14.29%). 25 patients in 49(51.02%) had total knee arthroplasty(TKA) and 10(40%) of those was bilateral. Mean age for bilateral TKA(56.35) was higher than unilateral(49.87). There was a statistically meaningful correlation between patient age and the patients with TKA (Spearman’s: rs = 0.338, p = 0.017). There were 2 revision surgeries out of 35 TKA (5.71%). Most of the patients had prophylactic factor treatment (43, 87.75%). Conclusion: Our study signify the high ratio of bilateral knee replacements in haemophilia A patients and how early age they progressed to KL stage 4 comparing to normal population. These results show the importance of patient care in this group of patients, close follow-up and prophylactic treatment. They should be managed in experienced centres by an experience team to decrease the risks and complications.https://dergipark.org.tr/tr/download/article-file/807357hemophiliaatotal knee arthroplastybilateralhemofili atotal diz artroplastisibilateral |
| spellingShingle | Levent Bayam Justine Theaker Sanat V Shah Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients Sakarya Tıp Dergisi hemophiliaa total knee arthroplasty bilateral hemofili a total diz artroplastisi bilateral |
| title | Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients |
| title_full | Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients |
| title_fullStr | Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients |
| title_full_unstemmed | Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients |
| title_short | Knee Arthropathy and Bilateral Total Knee Arthroplasty Ratio in Hemophilia A Patients |
| title_sort | knee arthropathy and bilateral total knee arthroplasty ratio in hemophilia a patients |
| topic | hemophiliaa total knee arthroplasty bilateral hemofili a total diz artroplastisi bilateral |
| url | https://dergipark.org.tr/tr/download/article-file/807357 |
| work_keys_str_mv | AT leventbayam kneearthropathyandbilateraltotalkneearthroplastyratioinhemophiliaapatients AT justinetheaker kneearthropathyandbilateraltotalkneearthroplastyratioinhemophiliaapatients AT sanatvshah kneearthropathyandbilateraltotalkneearthroplastyratioinhemophiliaapatients |