The Role of Periostin in Angiogenesis and Lymphangiogenesis in Tumors

The Role of Periostin in Angiogenesis and Lymphangiogenesis in Tumors

Periostin (POSTN) is a protein that is part of the extracellular matrix (ECM) and which significantly affects the control of intracellular signaling pathways (PI3K-AKT, FAK) through binding integrin receptors (αvβ3, αvβ5, α6β4). In addition, increased POSTN expression enhances the expression of VEGF...

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Bibliographic Details
Main Authors:	Adrian Wasik, Katarzyna Ratajczak-Wielgomas, Arkadiusz Badzinski, Piotr Dziegiel, Marzenna Podhorska-Okolow
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Cancers
Subjects:	periostin angiogenesis lymphangiogenesis vessels metastases epithelial-mesenchymal transition
Online Access:	https://www.mdpi.com/2072-6694/14/17/4225

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