Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft
Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs (<6 mm) after transplantation. Endothelialization of TEVGs is a key point to...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2021-08-01
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| Series: | Bioactive Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X20303467 |
| _version_ | 1797204328822341632 |
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| author | Qingjin Cai Wanshan Liao Fangchao Xue Xiaochen Wang Weiming Zhou Yanzhao Li Wen Zeng |
| author_facet | Qingjin Cai Wanshan Liao Fangchao Xue Xiaochen Wang Weiming Zhou Yanzhao Li Wen Zeng |
| author_sort | Qingjin Cai |
| collection | DOAJ |
| description | Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs (<6 mm) after transplantation. Endothelialization of TEVGs is a key point to prevent thrombosis. Here, we discuss different types of endothelialization and different seed cells of tissue-engineered vascular grafts. Meanwhile, endothelial heterogeneity is also discussed. Based on it, we provide a new perspective for selecting suitable types of endothelialization and suitable seed cells to improve the long-term patency rate of tissue-engineered vascular grafts with different diameters and lengths. |
| first_indexed | 2024-04-24T08:33:29Z |
| format | Article |
| id | doaj.art-73474e0d118b4c3c963b1b53ea6d064c |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:33:29Z |
| publishDate | 2021-08-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-73474e0d118b4c3c963b1b53ea6d064c2024-04-16T18:29:34ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2021-08-016825572568Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graftQingjin Cai0Wanshan Liao1Fangchao Xue2Xiaochen Wang3Weiming Zhou4Yanzhao Li5Wen Zeng6Department of Cell Biology, Third Military Medical University, Chongqing, 400038, ChinaDepartment of Cell Biology, Third Military Medical University, Chongqing, 400038, ChinaDepartment of Cell Biology, Third Military Medical University, Chongqing, 400038, ChinaDepartment of Cell Biology, Third Military Medical University, Chongqing, 400038, ChinaDepartment of Cell Biology, Third Military Medical University, Chongqing, 400038, ChinaState Key Laboratory of Trauma, Burn and Combined Injury, Chongqing, ChinaDepartment of Cell Biology, Third Military Medical University, Chongqing, 400038, China; State Key Laboratory of Trauma, Burn and Combined Injury, Chongqing, China; Departments of Neurology, Southwest Hospital, Third Military Medical University, Chongqing, China; Corresponding author. Department of Cell Biology, Third Military Medical University, Chongqing, 400038, China.Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular replacement therapy. However, thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs (<6 mm) after transplantation. Endothelialization of TEVGs is a key point to prevent thrombosis. Here, we discuss different types of endothelialization and different seed cells of tissue-engineered vascular grafts. Meanwhile, endothelial heterogeneity is also discussed. Based on it, we provide a new perspective for selecting suitable types of endothelialization and suitable seed cells to improve the long-term patency rate of tissue-engineered vascular grafts with different diameters and lengths.http://www.sciencedirect.com/science/article/pii/S2452199X20303467Tissue-engineered vascular graftsscaffold materialsseed cellsvascular endothelializationendothelial heterogeneity |
| spellingShingle | Qingjin Cai Wanshan Liao Fangchao Xue Xiaochen Wang Weiming Zhou Yanzhao Li Wen Zeng Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft Bioactive Materials Tissue-engineered vascular grafts scaffold materials seed cells vascular endothelialization endothelial heterogeneity |
| title | Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft |
| title_full | Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft |
| title_fullStr | Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft |
| title_full_unstemmed | Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft |
| title_short | Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft |
| title_sort | selection of different endothelialization modes and different seed cells for tissue engineered vascular graft |
| topic | Tissue-engineered vascular grafts scaffold materials seed cells vascular endothelialization endothelial heterogeneity |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X20303467 |
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