Hypermethylation of <i>UCHL1</i> Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN)

Hypermethylation of <i>UCHL1</i> Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN)

Epigenetic regulation plays an important role in the development and progression of nasopharyngeal carcinoma (NPC), but the epigenetic mechanisms underlying NPC metastasis remain poorly understood. Here, we demonstrate that hypermethylation of the <i>UCHL1</i> promoter leads to its downr...

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Bibliographic Details
Main Authors: Yin Zhao, Yuan Lei, Shi-Wei He, Ying-Qin Li, Ya-Qin Wang, Xiao-Hong Hong, Ye-Lin Liang, Jun-Yan Li, Yang Chen, Wei-Jie Luo, Pan-Pan Zhang, Xiao-Jing Yang, Qing-Mei He, Jun Ma, Na Liu, Ling-Long Tang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
nasopharyngeal carcinoma
uchl1
metastasis
methylation
cttn
Online Access:https://www.mdpi.com/2073-4409/9/3/559

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