Inhibition of Porcine Epidemic Diarrhea Virus by Cinchonine via Inducing Cellular Autophagy

Inhibition of Porcine Epidemic Diarrhea Virus by Cinchonine via Inducing Cellular Autophagy

Porcine epidemic diarrhea virus (PEDV) could cause lethal diarrhea and dehydration in suckling piglets, which can adversely affect the development of the global swine industry. The lack of effective therapeutical and prophylactic treatment especially for PEDV variant strains underlines the importanc...

Full description

Bibliographic Details
Main Authors:	Jingping Ren, Wei Zeng, Changsheng Jiang, Chang Li, Chengjun Zhang, Hua Cao, Wentao Li, Qigai He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	porcine epidemic diarrhea virus cinchonine antiviral autophagy endoplasmic reticulum (ER) stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.856711/full

Similar Items

Levistolide A Inhibits PEDV Replication via Inducing ROS Generation
by: Wei Zeng, et al.
Published: (2022-01-01)

Synthesis of Some Phenolic and Amino derivatives of Cinchoninic Acid
by: M. A. Al-Iraqi, et al.
Published: (2008-06-01)

Intermolecular Interactions in Molecular Ferroelectric Zinc Complexes of Cinchonine
by: Marko Očić, et al.
Published: (2024-11-01)

Development of a Genetically Engineered Bivalent Vaccine against Porcine Epidemic Diarrhea Virus and Porcine Rotavirus
by: Wan Li, et al.
Published: (2022-08-01)

Blood-stage antiplasmodial activity and oocyst formation-blockage of metallo copper-cinchonine complex
by: Camila Martins Gomes Morais, et al.
Published: (2022-12-01)

New Variants of Porcine Epidemic Diarrhea Virus, China, 2011
by: Wentao Li, et al.
Published: (2012-08-01)

Porcine epidemic diarrhea virus activates PERK-ROS axis to benefit its replication in Vero E6 cells
by: Yingshan Zhou, et al.
Published: (2023-02-01)

Transcriptome analysis of heat resistance regulated by quorum sensing system in Glaesserella parasuis
by: Bingzhou Zhang, et al.
Published: (2022-08-01)

A Systemic Study of Subcellular Localization of Porcine Epidemic Diarrhea Virus Proteins
by: Huixin Zhu, et al.
Published: (2022-12-01)

A portable transistor immunosensor for fast identification of porcine epidemic diarrhea virus
by: Xiao Hu, et al.
Published: (2024-05-01)

Endoplasmic reticulum homeostasis: a potential target for diabetic nephropathy
by: Ming Yang, et al.
Published: (2023-06-01)

Caerin1.1 Suppresses the Growth of Porcine Epidemic Diarrhea Virus In Vitro via Direct Binding to the Virus
by: Nan Guo, et al.
Published: (2018-09-01)

Endoplasmic reticulum stress and quality control in relation to cisplatin resistance in tumor cells
by: Wentao Mu, et al.
Published: (2024-06-01)

TurboID screening of ApxI toxin interactants identifies host proteins involved in Actinobacillus pleuropneumoniae-induced apoptosis of immortalized porcine alveolar macrophages
by: Yaofang Hu, et al.
Published: (2023-07-01)

Comparative Proteome Analysis of Porcine Jejunum Tissues in Response to a Virulent Strain of Porcine Epidemic Diarrhea Virus and Its Attenuated Strain
by: Zhonghua Li, et al.
Published: (2016-11-01)

Excessive ER-phagy mediated by FAM134B contributes to trophoblast cell mitochondrial dysfunction in preeclampsia
by: Wang Andi, et al.
Published: (2024-05-01)

Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018
by: Fanfan Zhang, et al.
Published: (2019-12-01)

Zearalenone induces apoptosis and autophagy by regulating endoplasmic reticulum stress signalling in porcine trophectoderm cells
by: Jun Bai, et al.
Published: (2023-03-01)

Cellular hnRNP A1 Interacts with Nucleocapsid Protein of Porcine Epidemic Diarrhea Virus and Impairs Viral Replication
by: Zhonghua Li, et al.
Published: (2018-03-01)

Cinchonine, a Potential Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist, Lowers Blood Glucose and Ameliorates Non-Alcoholic Steatohepatitis
by: Xue H, et al.
Published: (2023-05-01)

Nicotinamide Efficiently Suppresses Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus Replication
by: Mingxia Li, et al.
Published: (2023-07-01)

Epidemiological monitoring and genetic variation analysis of pathogens associated with porcine viral diarrhea in southern China from 2021 to 2023
by: Fanfan Zhang, et al.
Published: (2024-03-01)

Porcine Epidemic Diarrhea in Europe: In-Detail Analyses of Disease Dynamics and Molecular Epidemiology
by: Dennis Hanke, et al.
Published: (2017-07-01)

Porcine Epidemic Diarrhea Virus among Farmed Pigs, Ukraine
by: Akbar Dastjerdi, et al.
Published: (2015-12-01)

Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis
by: Qingling Yang, et al.
Published: (2019-07-01)

The dietary polysaccharide from Ommastrephes bartrami prevents chemotherapeutic mucositis by promoting the gene expression of antimicrobial peptides in Paneth cells
by: Tao Zuo, et al.
Published: (2015-01-01)

Melatonin Supplementation during <i>In Vitro</i> Maturation of Porcine Oocytes Alleviates Oxidative Stress and Endoplasmic Reticulum Stress Induced by Imidacloprid Exposure
by: Jing Wang, et al.
Published: (2023-08-01)

TurboID Screening of the OmpP2 Protein Reveals Host Proteins Involved in Recognition and Phagocytosis of Glaesserella parasuis by iPAM Cells
by: Changsheng Jiang, et al.
Published: (2022-10-01)

Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy
by: Ji Tu, et al.
Published: (2018-03-01)

Endoplasmic Reticulum-Shaping Atlastin Proteins Facilitate KSHV Replication
by: Wen-ying Long, et al.
Published: (2022-01-01)

Molecular Detection and Characterization of Porcine Epidemic Diarrhea Virus and Porcine Aichivirus C Coinfection in México
by: Montserrat-Elemi García-Hernández, et al.
Published: (2021-04-01)

Porcine Epidemic Diarrhea: Insights and Progress on Vaccines
by: Jung-Eun Park
Published: (2024-02-01)

Zearalenone Induces Apoptosis in Porcine Endometrial Stromal Cells through JNK Signaling Pathway Based on Endoplasmic Reticulum Stress
by: Jie Zhao, et al.
Published: (2022-11-01)

Hypericum japonicum extract inhibited porcine epidemic diarrhea virus in vitro and in vivo
by: Hongyu Rao, et al.
Published: (2023-04-01)

Efficacy of genogroup 1 based porcine epidemic diarrhea live vaccine against genogroup 2 field strain in Japan
by: Tetsuo Sato, et al.
Published: (2018-02-01)

Porcine Circovirus Type 3 in Pig Farms Experiencing Diarrhea in Jiangxi, China: Prevalence, Genome Sequence and Pathogenicity
by: Fanfan Zhang, et al.
Published: (2020-12-01)

Isolation and characterization of a variant porcine epidemic diarrhea virus in China
by: Pan Yongfei, et al.
Published: (2012-09-01)

The structure and function of mitochondria-associated endoplasmic reticulum membranes and their role in pancreatic β-cells dysregulation
by: Olena Kaniuka, et al.
Published: (2023-12-01)

The Sec61 translocon limits IRE1α signaling during the unfolded protein response
by: Arunkumar Sundaram, et al.
Published: (2017-05-01)

The Endoplasmic Reticulum Is a Key Battleground between Phytoplasma Aggression and Host Plant Defense
by: Junichi Inaba, et al.
Published: (2023-08-01)