Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia
The Thoroughbred (TB) horse has hugely impacted the development of horse breeding around the world. This breed has unique genetic qualities due to having had a closed studbook for approximately 300 years. In Russia, TBs have been bred since the second half of the 18th century. Here, we analyzed the...
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MDPI AG
2020-07-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/10/7/1217 |
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| author | Valery Kalashnikov Lyudmila Khrabrova Nina Blohina Alexander Zaitcev Tatyana Kalashnikova |
| author_facet | Valery Kalashnikov Lyudmila Khrabrova Nina Blohina Alexander Zaitcev Tatyana Kalashnikova |
| author_sort | Valery Kalashnikov |
| collection | DOAJ |
| description | The Thoroughbred (TB) horse has hugely impacted the development of horse breeding around the world. This breed has unique genetic qualities due to having had a closed studbook for approximately 300 years. In Russia, TBs have been bred since the second half of the 18th century. Here, we analyzed the genetic diversity and the inbreeding level in TB horses (<i>n</i> = 9680) for the period from 1990 to 2018 using polymorphisms of 17 microsatellite loci. We found that the genetic structure of the TB breed in Russia is represented by 100 alleles of panel STR (short tandem repeat) loci and has been stable for the past three decades. The conducted monitoring revealed a slight increase in the Wright’s inbreeding coefficient in all age and sex groups of TB horses (stallions, broodmares, and foals) from 0.68% to 0.90%, which was followed by a decrease in the degree of heterozygosity, Ho, from 68.5% to 67.6%. The Spearman’s rank correlation coefficient between the level of inbreeding and the degree of homozygosity was estimated (<i>r</i> = 0.022; <i>p</i> > 0.05). The obtained data on the DNA genotypes of horses of different breeds provide a unique base for the evaluation of genetic variability and the control of genetic variability of horses in selection programs. |
| first_indexed | 2024-03-10T18:24:45Z |
| format | Article |
| id | doaj.art-7348859bb93f42f792af52992e2ec590 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T18:24:45Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-7348859bb93f42f792af52992e2ec5902023-11-20T07:04:53ZengMDPI AGAnimals2076-26152020-07-01107121710.3390/ani10071217Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in RussiaValery Kalashnikov0Lyudmila Khrabrova1Nina Blohina2Alexander Zaitcev3Tatyana Kalashnikova4The All-Russian Research Institute for Horse Breeding, Ryazan region, 391105 Rybnoe, RussiaThe All-Russian Research Institute for Horse Breeding, Ryazan region, 391105 Rybnoe, RussiaThe All-Russian Research Institute for Horse Breeding, Ryazan region, 391105 Rybnoe, RussiaThe All-Russian Research Institute for Horse Breeding, Ryazan region, 391105 Rybnoe, RussiaThe All-Russian Research Institute for Horse Breeding, Ryazan region, 391105 Rybnoe, RussiaThe Thoroughbred (TB) horse has hugely impacted the development of horse breeding around the world. This breed has unique genetic qualities due to having had a closed studbook for approximately 300 years. In Russia, TBs have been bred since the second half of the 18th century. Here, we analyzed the genetic diversity and the inbreeding level in TB horses (<i>n</i> = 9680) for the period from 1990 to 2018 using polymorphisms of 17 microsatellite loci. We found that the genetic structure of the TB breed in Russia is represented by 100 alleles of panel STR (short tandem repeat) loci and has been stable for the past three decades. The conducted monitoring revealed a slight increase in the Wright’s inbreeding coefficient in all age and sex groups of TB horses (stallions, broodmares, and foals) from 0.68% to 0.90%, which was followed by a decrease in the degree of heterozygosity, Ho, from 68.5% to 67.6%. The Spearman’s rank correlation coefficient between the level of inbreeding and the degree of homozygosity was estimated (<i>r</i> = 0.022; <i>p</i> > 0.05). The obtained data on the DNA genotypes of horses of different breeds provide a unique base for the evaluation of genetic variability and the control of genetic variability of horses in selection programs.https://www.mdpi.com/2076-2615/10/7/1217genetic parametersgenetic diversityinbreedinghorseThoroughbred |
| spellingShingle | Valery Kalashnikov Lyudmila Khrabrova Nina Blohina Alexander Zaitcev Tatyana Kalashnikova Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia Animals genetic parameters genetic diversity inbreeding horse Thoroughbred |
| title | Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia |
| title_full | Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia |
| title_fullStr | Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia |
| title_full_unstemmed | Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia |
| title_short | Dynamics of the Inbreeding Coefficient and Homozygosity in Thoroughbred Horses in Russia |
| title_sort | dynamics of the inbreeding coefficient and homozygosity in thoroughbred horses in russia |
| topic | genetic parameters genetic diversity inbreeding horse Thoroughbred |
| url | https://www.mdpi.com/2076-2615/10/7/1217 |
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