Microwave-Assisted Synthesis of (Piperidin-1-yl)quinolin-3-yl)methylene)hydrazinecarbothioamides as Potent Inhibitors of Cholinesterases: A Biochemical and In Silico Approach

Microwave-Assisted Synthesis of (Piperidin-1-yl)quinolin-3-yl)methylene)hydrazinecarbothioamides as Potent Inhibitors of Cholinesterases: A Biochemical and In Silico Approach

Alzheimer’s disease (AD), a progressive neurodegenerative disorder, characterized by central cognitive dysfunction, memory loss, and intellectual decline poses a major public health problem affecting millions of people around the globe. Despite several clinically approved drugs and development of an...

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Bibliographic Details
Main Authors: Rubina Munir, Muhammad Zia-ur-Rehman, Shahzad Murtaza, Sumera Zaib, Noman Javid, Sana Javaid Awan, Kiran Iftikhar, Muhammad Makshoof Athar, Imtiaz Khan
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
quinoline
piperidine
thiosemicarbazone
carbothioamide
Alzheimer’s disease
neurodegeneration
Online Access:https://www.mdpi.com/1420-3049/26/3/656

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