A Structural Perspective of the Role of IP6 in Immature and Mature Retroviral Assembly

The small cellular molecule inositol hexakisphosphate (IP6) has been known for ~20 years to promote the in vitro assembly of HIV-1 into immature virus-like particles. However, the molecular details underlying this effect have been determined only recently, with the identification of the IP6 binding...

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Bibliographic Details
Main Authors: Martin Obr, Florian K. M. Schur, Robert A. Dick
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/9/1853