Imiquimod 5% cream in topical treatment of facial basal cell carcinoma

Introduction: Basal Cell Carcinoma (BCC) is a non-melanocytic skin neoplasm originating from the cells in the basal epidermal layer, hair follicle shell or other skin adnexa. It is the most frequent skin malignancy. Treatment is surgical or nonsurgical. Cases reports: Herein we present 2 patients wi...

Full description

Bibliographic Details
Main Authors: Grubor Svetlana D., Tatljak-Vlahović Vesna J., Radojević Biljana P.
Format: Article
Language:English
Published: Srpsko lekarsko drustvo 2015-01-01
Series:Hospital Pharmacology
Subjects:
Online Access:http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2015/2334-94921501184G.pdf
_version_ 1828767747628072960
author Grubor Svetlana D.
Tatljak-Vlahović Vesna J.
Radojević Biljana P.
author_facet Grubor Svetlana D.
Tatljak-Vlahović Vesna J.
Radojević Biljana P.
author_sort Grubor Svetlana D.
collection DOAJ
description Introduction: Basal Cell Carcinoma (BCC) is a non-melanocytic skin neoplasm originating from the cells in the basal epidermal layer, hair follicle shell or other skin adnexa. It is the most frequent skin malignancy. Treatment is surgical or nonsurgical. Cases reports: Herein we present 2 patients with superficial type of BCC and actinic keratosis of the face. The patients have been diagnosed by dermoscopy DermLite dermatoscope by 3Gen Inc. manufacturer, and skin biopsy has been performed for histopathological examination. The superficial BCC of the face has been treated with 5% Imiquimod cream once a day for 5 days in a week, during 4 weeks, with erosions and crusts until complete skin restoration. Conclusion: Based on these case reports, it could be concluded that 5% Imiquimod cream is safe and effective treatment for superficial BCC and represents an optimal treatment to achieve good clinical and esthetic effect for the patients.
first_indexed 2024-12-11T07:33:18Z
format Article
id doaj.art-735561b2c460483698e4af3673adf921
institution Directory Open Access Journal
issn 2334-9492
2334-9492
language English
last_indexed 2024-12-11T07:33:18Z
publishDate 2015-01-01
publisher Srpsko lekarsko drustvo
record_format Article
series Hospital Pharmacology
spelling doaj.art-735561b2c460483698e4af3673adf9212022-12-22T01:15:46ZengSrpsko lekarsko drustvoHospital Pharmacology2334-94922334-94922015-01-012118418810.5937/hpimj1501184G2334-94921501184GImiquimod 5% cream in topical treatment of facial basal cell carcinomaGrubor Svetlana D.0Tatljak-Vlahović Vesna J.1Radojević Biljana P.2University of Belgrade, Faculty of Medicine - Clinical Center 'Zemun', Belgrade-Zemun, SerbiaCity Department of Dermatovenerology, BelgradeUniversity of Belgrade, Faculty of Medicine - Clinical Center 'Zemun', Belgrade-Zemun, SerbiaIntroduction: Basal Cell Carcinoma (BCC) is a non-melanocytic skin neoplasm originating from the cells in the basal epidermal layer, hair follicle shell or other skin adnexa. It is the most frequent skin malignancy. Treatment is surgical or nonsurgical. Cases reports: Herein we present 2 patients with superficial type of BCC and actinic keratosis of the face. The patients have been diagnosed by dermoscopy DermLite dermatoscope by 3Gen Inc. manufacturer, and skin biopsy has been performed for histopathological examination. The superficial BCC of the face has been treated with 5% Imiquimod cream once a day for 5 days in a week, during 4 weeks, with erosions and crusts until complete skin restoration. Conclusion: Based on these case reports, it could be concluded that 5% Imiquimod cream is safe and effective treatment for superficial BCC and represents an optimal treatment to achieve good clinical and esthetic effect for the patients.http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2015/2334-94921501184G.pdfbasal cell carcinomaactinic keratosisimiquimodtoll-like receptor
spellingShingle Grubor Svetlana D.
Tatljak-Vlahović Vesna J.
Radojević Biljana P.
Imiquimod 5% cream in topical treatment of facial basal cell carcinoma
Hospital Pharmacology
basal cell carcinoma
actinic keratosis
imiquimod
toll-like receptor
title Imiquimod 5% cream in topical treatment of facial basal cell carcinoma
title_full Imiquimod 5% cream in topical treatment of facial basal cell carcinoma
title_fullStr Imiquimod 5% cream in topical treatment of facial basal cell carcinoma
title_full_unstemmed Imiquimod 5% cream in topical treatment of facial basal cell carcinoma
title_short Imiquimod 5% cream in topical treatment of facial basal cell carcinoma
title_sort imiquimod 5 cream in topical treatment of facial basal cell carcinoma
topic basal cell carcinoma
actinic keratosis
imiquimod
toll-like receptor
url http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2015/2334-94921501184G.pdf
work_keys_str_mv AT gruborsvetlanad imiquimod5creamintopicaltreatmentoffacialbasalcellcarcinoma
AT tatljakvlahovicvesnaj imiquimod5creamintopicaltreatmentoffacialbasalcellcarcinoma
AT radojevicbiljanap imiquimod5creamintopicaltreatmentoffacialbasalcellcarcinoma