Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report
Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an int...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-12-01
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| Series: | Mayo Clinic Proceedings: Innovations, Quality & Outcomes |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2542454819301493 |
| _version_ | 1819228330676715520 |
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| author | Nazanin Yeganeh Kazemi, BS Christopher Jain, MD Melanie C. Bois, MD Atta Behfar, MD, PhD Kenneth Olivier, MD Svetomir N. Markovic, MD, PhD |
| author_facet | Nazanin Yeganeh Kazemi, BS Christopher Jain, MD Melanie C. Bois, MD Atta Behfar, MD, PhD Kenneth Olivier, MD Svetomir N. Markovic, MD, PhD |
| author_sort | Nazanin Yeganeh Kazemi, BS |
| collection | DOAJ |
| description | Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an interatrial mass. Temporary pacing was required before biopsy, which revealed metastatic MCC. Treatment included permanent pacing, anti–programmed cell death ligand 1 immunotherapy, and radiation to the heart resulting in notable decrease in tumor size and normalized cardiac rhythm. |
| first_indexed | 2024-12-23T10:55:34Z |
| format | Article |
| id | doaj.art-735a8d83092744ab8097f935fc3017fe |
| institution | Directory Open Access Journal |
| issn | 2542-4548 |
| language | English |
| last_indexed | 2024-12-23T10:55:34Z |
| publishDate | 2019-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Mayo Clinic Proceedings: Innovations, Quality & Outcomes |
| spelling | doaj.art-735a8d83092744ab8097f935fc3017fe2022-12-21T17:49:47ZengElsevierMayo Clinic Proceedings: Innovations, Quality & Outcomes2542-45482019-12-0134510516Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case ReportNazanin Yeganeh Kazemi, BS0Christopher Jain, MD1Melanie C. Bois, MD2Atta Behfar, MD, PhD3Kenneth Olivier, MD4Svetomir N. Markovic, MD, PhD5Medical Scientist Training Program, Mayo Clinic, Rochester, MNDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MNDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MNDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MNDepartment of Radiation Oncology, Mayo Clinic, Rochester, MNDepartment of Oncology, Mayo Clinic, Rochester, MN; Correspondence: Address to Svetomir N. Markovic, MD, PhD, Department of Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905Merkel cell carcinoma (MCC) is a rare, rapidly proliferating skin cancer that commonly metastasizes to regional lymph nodes. We present the case of a 73-year-old woman with a history of MCC and non-Hodgkin B-cell lymphoma who presented with second-degree heart block (Mobitz type II) caused by an interatrial mass. Temporary pacing was required before biopsy, which revealed metastatic MCC. Treatment included permanent pacing, anti–programmed cell death ligand 1 immunotherapy, and radiation to the heart resulting in notable decrease in tumor size and normalized cardiac rhythm.http://www.sciencedirect.com/science/article/pii/S2542454819301493 |
| spellingShingle | Nazanin Yeganeh Kazemi, BS Christopher Jain, MD Melanie C. Bois, MD Atta Behfar, MD, PhD Kenneth Olivier, MD Svetomir N. Markovic, MD, PhD Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report Mayo Clinic Proceedings: Innovations, Quality & Outcomes |
| title | Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report |
| title_full | Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report |
| title_fullStr | Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report |
| title_full_unstemmed | Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report |
| title_short | Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report |
| title_sort | heart block caused by cardiac metastasis from merkel cell carcinoma a case report |
| url | http://www.sciencedirect.com/science/article/pii/S2542454819301493 |
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