Stem cell therapy - Hope and scope in pediatric surgery

A stem cell is an undifferentiated cell in the body with undetermined function capable of forming various tissues under definite signals received from the body. Stem cell research in animals using embryonal stem cells has been an ongoing program in the west with fruitful results. However, only limit...

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Main Authors: Gupta Devendra, Sharma Shilpa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2005-01-01
Series:Journal of Indian Association of Pediatric Surgeons
Subjects:
Online Access:http://www.jiaps.com/article.asp?issn=0971-9261;year=2005;volume=10;issue=3;spage=138;epage=141;aulast=Gupta
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author Gupta Devendra
Sharma Shilpa
author_facet Gupta Devendra
Sharma Shilpa
author_sort Gupta Devendra
collection DOAJ
description A stem cell is an undifferentiated cell in the body with undetermined function capable of forming various tissues under definite signals received from the body. Stem cell research in animals using embryonal stem cells has been an ongoing program in the west with fruitful results. However, only limited information is available with the use of stem cells in human beings. Of the various sources of stem cells, umbilical cord blood stem cell research has shown potential for future treatment in Alzheimer′s, Parkinson′s, heart attack, stroke and spinal cord injuries. Human trials have been done in diseases like spinal cord injury and chronic liver cirrhosis. Cord blood stem cells have already been effectively used in the treatment of sickle cell, leukemia, non-Hodgkin′s lymphoma and some other cancers, life threatening anemias and auto-immune diseases. Current challenges with the use of stem cells in clinical practice include the provisions to direct the differentiation of embryonic stem cells into specialized cell populations, and also devise ways to guard their development or proliferation once placed in vivo. Only further research and its clinical application will solve the many unanswered queries.
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spelling doaj.art-735ccdeb3f4e48769b4ad4b2538255f02022-12-21T23:32:04ZengWolters Kluwer Medknow PublicationsJournal of Indian Association of Pediatric Surgeons0971-92612005-01-01103138141Stem cell therapy - Hope and scope in pediatric surgeryGupta DevendraSharma ShilpaA stem cell is an undifferentiated cell in the body with undetermined function capable of forming various tissues under definite signals received from the body. Stem cell research in animals using embryonal stem cells has been an ongoing program in the west with fruitful results. However, only limited information is available with the use of stem cells in human beings. Of the various sources of stem cells, umbilical cord blood stem cell research has shown potential for future treatment in Alzheimer′s, Parkinson′s, heart attack, stroke and spinal cord injuries. Human trials have been done in diseases like spinal cord injury and chronic liver cirrhosis. Cord blood stem cells have already been effectively used in the treatment of sickle cell, leukemia, non-Hodgkin′s lymphoma and some other cancers, life threatening anemias and auto-immune diseases. Current challenges with the use of stem cells in clinical practice include the provisions to direct the differentiation of embryonic stem cells into specialized cell populations, and also devise ways to guard their development or proliferation once placed in vivo. Only further research and its clinical application will solve the many unanswered queries.http://www.jiaps.com/article.asp?issn=0971-9261;year=2005;volume=10;issue=3;spage=138;epage=141;aulast=GuptaStem cellPeduatric SurgeryBiliary atresiaSpina bifida
spellingShingle Gupta Devendra
Sharma Shilpa
Stem cell therapy - Hope and scope in pediatric surgery
Journal of Indian Association of Pediatric Surgeons
Stem cell
Peduatric Surgery
Biliary atresia
Spina bifida
title Stem cell therapy - Hope and scope in pediatric surgery
title_full Stem cell therapy - Hope and scope in pediatric surgery
title_fullStr Stem cell therapy - Hope and scope in pediatric surgery
title_full_unstemmed Stem cell therapy - Hope and scope in pediatric surgery
title_short Stem cell therapy - Hope and scope in pediatric surgery
title_sort stem cell therapy hope and scope in pediatric surgery
topic Stem cell
Peduatric Surgery
Biliary atresia
Spina bifida
url http://www.jiaps.com/article.asp?issn=0971-9261;year=2005;volume=10;issue=3;spage=138;epage=141;aulast=Gupta
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