Targeting tumor-associated macrophages for the immunotherapy of glioblastoma: Navigating the clinical and translational landscape

Targeting tumor-associated macrophages for the immunotherapy of glioblastoma: Navigating the clinical and translational landscape

Tumor-associated macrophages (TAMs) can directly clear tumor cells and enhance the phagocytic ability of immune cells. An abundance of TAMs at the site of the glioblastoma tumor indicates that TAM-targeting immunotherapy could represent a potential form of treatment for this aggressive cancer. Herei...

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Bibliographic Details
Main Authors: Zide Wang, Hanlin Zhong, Xiaohong Liang, Shilei Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
glioblastoma
tumor-associated macrophage
immunotherapy
tumor microenvironment
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1024921/full

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