The chaperone system in glioblastoma multiforme and derived cell lines: diagnostic and mechanistic implications

The chaperone system in glioblastoma multiforme and derived cell lines: diagnostic and mechanistic implications

Background: Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor in adults. Novel treatments are needed to counteract the molecular mechanisms of GBM growth and drug resistance. The chaperone system (CS) members are typically cytoprotective but some, termed Hsp, can bec...

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Bibliographic Details
Main Authors: Giusi Alberti, Claudia Campanella, Letizia Paladino, Rossana Porcasi, Celeste Caruso Bavisotto, Alessandro Pitruzzella, Francesca Graziano, Ada Maria Florena, Antonina Argo, Everly Conway de Macario, Alberto JL Macario, Francesco Cappello, Fabio Bucchieri, Rosario Barone, Francesca Rappa
Format: Article
Language:English
Published: IMR Press 2022-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
glioblastoma multiforme (gbm)
chaperone system (cs)
heat shock protein (hsp)
vascular endothelial growth factor (vegf)
gmb cell lines
Online Access:https://www.imrpress.com/journal/FBL/27/3/10.31083/j.fbl2703097

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