Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics
Rapid development of versatile layer-by-layer technology has resulted in important breakthroughs in the understanding of the nature of molecular interactions in multilayer assemblies made of polyelectrolytes. Nowadays, polyelectrolyte multilayers (PEM) are considered to be non-equilibrium and highly...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/12/9/1949 |
| _version_ | 1797555260968927232 |
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| author | Jack Campbell Anna S. Vikulina |
| author_facet | Jack Campbell Anna S. Vikulina |
| author_sort | Jack Campbell |
| collection | DOAJ |
| description | Rapid development of versatile layer-by-layer technology has resulted in important breakthroughs in the understanding of the nature of molecular interactions in multilayer assemblies made of polyelectrolytes. Nowadays, polyelectrolyte multilayers (PEM) are considered to be non-equilibrium and highly dynamic structures. High interest in biomedical applications of PEMs has attracted attention to PEMs made of biopolymers. Recent studies suggest that biopolymer dynamics determines the fate and the properties of such PEMs; however, deciphering, predicting and controlling the dynamics of polymers remains a challenge. This review brings together the up-to-date knowledge of the role of molecular dynamics in multilayers assembled from biopolymers. We discuss how molecular dynamics determines the properties of these PEMs from the nano to the macro scale, focusing on its role in PEM formation and non-enzymatic degradation. We summarize the factors allowing the control of molecular dynamics within PEMs, and therefore to tailor polymer multilayers on demand. |
| first_indexed | 2024-03-10T16:44:55Z |
| format | Article |
| id | doaj.art-736004b90db0473eb6865363a0bd9f4e |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T16:44:55Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-736004b90db0473eb6865363a0bd9f4e2023-11-20T11:43:51ZengMDPI AGPolymers2073-43602020-08-01129194910.3390/polym12091949Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular DynamicsJack Campbell0Anna S. Vikulina1School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UKFraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses, Am Mühlenberg 13, 14476 Potsdam-Golm, GermanyRapid development of versatile layer-by-layer technology has resulted in important breakthroughs in the understanding of the nature of molecular interactions in multilayer assemblies made of polyelectrolytes. Nowadays, polyelectrolyte multilayers (PEM) are considered to be non-equilibrium and highly dynamic structures. High interest in biomedical applications of PEMs has attracted attention to PEMs made of biopolymers. Recent studies suggest that biopolymer dynamics determines the fate and the properties of such PEMs; however, deciphering, predicting and controlling the dynamics of polymers remains a challenge. This review brings together the up-to-date knowledge of the role of molecular dynamics in multilayers assembled from biopolymers. We discuss how molecular dynamics determines the properties of these PEMs from the nano to the macro scale, focusing on its role in PEM formation and non-enzymatic degradation. We summarize the factors allowing the control of molecular dynamics within PEMs, and therefore to tailor polymer multilayers on demand.https://www.mdpi.com/2073-4360/12/9/1949polyelectrolyte multilayersthin filmsdiffusionfilm growthdegradation |
| spellingShingle | Jack Campbell Anna S. Vikulina Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics Polymers polyelectrolyte multilayers thin films diffusion film growth degradation |
| title | Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics |
| title_full | Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics |
| title_fullStr | Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics |
| title_full_unstemmed | Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics |
| title_short | Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics |
| title_sort | layer by layer assemblies of biopolymers build up mechanical stability and molecular dynamics |
| topic | polyelectrolyte multilayers thin films diffusion film growth degradation |
| url | https://www.mdpi.com/2073-4360/12/9/1949 |
| work_keys_str_mv | AT jackcampbell layerbylayerassembliesofbiopolymersbuildupmechanicalstabilityandmoleculardynamics AT annasvikulina layerbylayerassembliesofbiopolymersbuildupmechanicalstabilityandmoleculardynamics |