Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient
61-year-old man, with a history of years of unknown etiology bronchiectasis, with chronic bronchial infection by Burkholderia multivorans, who received treatment with a double lung transplant on 08/20/2020. Persistent positive cultures of Burkholderia multivorans after transplant in respiratory samp...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007122000065 |
| _version_ | 1819079143851032576 |
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| author | Víctor M. Mora Cuesta Noelia Borja Vargas David Iturbe Fernández Sandra Tello Mena José M. Cifrián Martínez |
| author_facet | Víctor M. Mora Cuesta Noelia Borja Vargas David Iturbe Fernández Sandra Tello Mena José M. Cifrián Martínez |
| author_sort | Víctor M. Mora Cuesta |
| collection | DOAJ |
| description | 61-year-old man, with a history of years of unknown etiology bronchiectasis, with chronic bronchial infection by Burkholderia multivorans, who received treatment with a double lung transplant on 08/20/2020. Persistent positive cultures of Burkholderia multivorans after transplant in respiratory samples was observed, and treatment with inhaled tobramycin 300 mg/12 hours was started. One month after treatment, a significant worsening of renal function was observed, which was already altered, and toxic levels of tobramycin were measured in blood samples 12 hours after the last inhaled administration. After stopping treatment, kidney function returned to its baseline values. |
| first_indexed | 2024-12-21T19:24:18Z |
| format | Article |
| id | doaj.art-7360e2b2911a4e478c011ff68e1aa4bf |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-21T19:24:18Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-7360e2b2911a4e478c011ff68e1aa4bf2022-12-21T18:52:53ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0136101584Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patientVíctor M. Mora Cuesta0Noelia Borja Vargas1David Iturbe Fernández2Sandra Tello Mena3José M. Cifrián Martínez4Corresponding author. Marqués de Valdecilla University Hospital, Pneumology department, Lung Transplant Unit, Avda. Valdecilla n° 25, ZP: 39008, Santander, Cantabria, Spain.; Marqués de Valdecilla University Hospital, Pneumology department, Lung Transplant Unit, Avda. Valdecilla n° 25, ZP: 39008, Santander, Cantabria, SpainMarqués de Valdecilla University Hospital, Pneumology department, Lung Transplant Unit, Avda. Valdecilla n° 25, ZP: 39008, Santander, Cantabria, SpainMarqués de Valdecilla University Hospital, Pneumology department, Lung Transplant Unit, Avda. Valdecilla n° 25, ZP: 39008, Santander, Cantabria, SpainMarqués de Valdecilla University Hospital, Pneumology department, Lung Transplant Unit, Avda. Valdecilla n° 25, ZP: 39008, Santander, Cantabria, SpainMarqués de Valdecilla University Hospital, Pneumology department, Lung Transplant Unit, Avda. Valdecilla n° 25, ZP: 39008, Santander, Cantabria, Spain61-year-old man, with a history of years of unknown etiology bronchiectasis, with chronic bronchial infection by Burkholderia multivorans, who received treatment with a double lung transplant on 08/20/2020. Persistent positive cultures of Burkholderia multivorans after transplant in respiratory samples was observed, and treatment with inhaled tobramycin 300 mg/12 hours was started. One month after treatment, a significant worsening of renal function was observed, which was already altered, and toxic levels of tobramycin were measured in blood samples 12 hours after the last inhaled administration. After stopping treatment, kidney function returned to its baseline values.http://www.sciencedirect.com/science/article/pii/S2213007122000065Lung transplantationRenal failureInhaled tobramycin |
| spellingShingle | Víctor M. Mora Cuesta Noelia Borja Vargas David Iturbe Fernández Sandra Tello Mena José M. Cifrián Martínez Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient Respiratory Medicine Case Reports Lung transplantation Renal failure Inhaled tobramycin |
| title | Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient |
| title_full | Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient |
| title_fullStr | Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient |
| title_full_unstemmed | Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient |
| title_short | Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient |
| title_sort | exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient |
| topic | Lung transplantation Renal failure Inhaled tobramycin |
| url | http://www.sciencedirect.com/science/article/pii/S2213007122000065 |
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