Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin
Objectives: The aim of this study was to evaluate the effect of dentin remineralization using proanthocyanidin (PA), fluoride varnish and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste and their various combinations on microhardness of demineralized root dentin. Materials and Meth...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2017-08-01
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| Series: | Frontiers in Dentistry |
| Subjects: | |
| Online Access: | https://jdt.tums.ac.ir/index.php/jdt/article/view/1697 |
| _version_ | 1818530815232966656 |
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| author | Zahra Khamverdi Matin Kordestani Alireza Soltanian |
| author_facet | Zahra Khamverdi Matin Kordestani Alireza Soltanian |
| author_sort | Zahra Khamverdi |
| collection | DOAJ |
| description | Objectives: The aim of this study was to evaluate the effect of dentin remineralization using proanthocyanidin (PA), fluoride varnish and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste and their various combinations on microhardness of demineralized root dentin.
Materials and Methods: One-hundred and twenty freshly extracted sound human premolars were selected and randomly divided into eight groups for dentin treatment as follows. C: Deionized water (control); PA: 6.5% PA solution; F: fluoride varnish (5% NaF, 22600 ppm fluoride); CP: CCP-ACP; PAF: 6.5% PA + fluoride varnish; PACP: 6.5% PA + CCP-ACP; FCP: fluoride varnish + CCP-ACP and PAFCP: 6.5% PA + fluoride varnish + CCP-ACP. All specimens were subjected to Vickers microhardness test (500 g, 10 seconds, 3 points). Data were analyzed using one-way ANOVA and Tukey’s post hoc test. The significance level was set at 0.05.
Results: The mean and standard deviation (SD) values of Vickers hardness number (VHN) in groups C, PA, F, CP, PAF, PACP, FCP and PAFCP were 37.39±4.97, 38.68±4.62, 48.28±2.68 ,41.91±3.32, 48.59±2.55, 53.34±2.57, 48.413±4.00 and 55.20±1.82, respectively. Pairwise comparisons of the groups revealed that there was no significant difference between groups C and PA, PA and CP, F and PAF, F and FCP, PAF and FCP, and PACP and FPACP (P>0.05); but significant differences were observed between other groups (P<0.05).
Conclusions: The results of this study showed that the tested dentin treatments increased the microhardness of demineralized root dentin except for PA application. |
| first_indexed | 2024-12-11T17:24:28Z |
| format | Article |
| id | doaj.art-7362961878eb4ccdb0b5abd0d8b47300 |
| institution | Directory Open Access Journal |
| issn | 2676-296X |
| language | English |
| last_indexed | 2024-12-11T17:24:28Z |
| publishDate | 2017-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Frontiers in Dentistry |
| spelling | doaj.art-7362961878eb4ccdb0b5abd0d8b473002022-12-22T00:57:02ZengTehran University of Medical SciencesFrontiers in Dentistry2676-296X2017-08-01142910Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized DentinZahra Khamverdi0Matin Kordestani1Alireza Soltanian2Professor, Dental Research Center, Department of Restorative Dentistry, Dental School, Hamadan University of Medical Sciences, Hamadan, IranPost Graduate Student, Department of Restorative Dentistry, Dental School, Hamadan University of Medical Sciences, Hamadan, IranProfessor, Department of Biostatiatics, School of Public Health and Modeling of Noncomunicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, IranObjectives: The aim of this study was to evaluate the effect of dentin remineralization using proanthocyanidin (PA), fluoride varnish and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste and their various combinations on microhardness of demineralized root dentin. Materials and Methods: One-hundred and twenty freshly extracted sound human premolars were selected and randomly divided into eight groups for dentin treatment as follows. C: Deionized water (control); PA: 6.5% PA solution; F: fluoride varnish (5% NaF, 22600 ppm fluoride); CP: CCP-ACP; PAF: 6.5% PA + fluoride varnish; PACP: 6.5% PA + CCP-ACP; FCP: fluoride varnish + CCP-ACP and PAFCP: 6.5% PA + fluoride varnish + CCP-ACP. All specimens were subjected to Vickers microhardness test (500 g, 10 seconds, 3 points). Data were analyzed using one-way ANOVA and Tukey’s post hoc test. The significance level was set at 0.05. Results: The mean and standard deviation (SD) values of Vickers hardness number (VHN) in groups C, PA, F, CP, PAF, PACP, FCP and PAFCP were 37.39±4.97, 38.68±4.62, 48.28±2.68 ,41.91±3.32, 48.59±2.55, 53.34±2.57, 48.413±4.00 and 55.20±1.82, respectively. Pairwise comparisons of the groups revealed that there was no significant difference between groups C and PA, PA and CP, F and PAF, F and FCP, PAF and FCP, and PACP and FPACP (P>0.05); but significant differences were observed between other groups (P<0.05). Conclusions: The results of this study showed that the tested dentin treatments increased the microhardness of demineralized root dentin except for PA application.https://jdt.tums.ac.ir/index.php/jdt/article/view/1697DentinFluorideProanthocyanidinRemineralization |
| spellingShingle | Zahra Khamverdi Matin Kordestani Alireza Soltanian Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin Frontiers in Dentistry Dentin Fluoride Proanthocyanidin Remineralization |
| title | Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin |
| title_full | Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin |
| title_fullStr | Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin |
| title_full_unstemmed | Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin |
| title_short | Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin |
| title_sort | effect of proanthocyanidin fluoride and casein phosphopeptide amorphous calcium phosphate remineralizing agents on microhardness of demineralized dentin |
| topic | Dentin Fluoride Proanthocyanidin Remineralization |
| url | https://jdt.tums.ac.ir/index.php/jdt/article/view/1697 |
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