Targeted delivery of hyaluronic acid-coated solid lipid nanoparticles for rheumatoid arthritis therapy

Targeted delivery of hyaluronic acid-coated solid lipid nanoparticles for rheumatoid arthritis therapy

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease. Long-term, high-dose glucocorticoid therapy can be used to treat the disease, but the fact that the drug distributes systemically can give rise to severe adverse effects. Here we develop a targeted system for treating RA in which...

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Bibliographic Details
Main Authors: Meiling Zhou, Jierong Hou, Zhirong Zhong, Na Hao, Yan Lin, Chunhong Li
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
rheumatoid arthritis
hyaluronic acid
solid lipid nanoparticles
drug delivery
prednisolone
Online Access:http://dx.doi.org/10.1080/10717544.2018.1447050

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