Diagnosing peri-implant disease using the tongue as a 24/7 detector
Early detection of gum inflammation caused by dental implants helps prevent tissue damage. Here, the authors present a peptide sensor that generates a bitter taste when cleaved by proteases present in peri-implant disease, embed it in a chewing gum, and compare the probe to existing sensors using pa...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00340-x |
| _version_ | 1818428958086004736 |
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| author | J. Ritzer T. Lühmann C. Rode M. Pein-Hackelbusch I. Immohr U. Schedler T. Thiele S. Stübinger B. v. Rechenberg J. Waser-Althaus F. Schlottig M. Merli H. Dawe M. Karpíšek R. Wyrwa M. Schnabelrauch L. Meinel |
| author_facet | J. Ritzer T. Lühmann C. Rode M. Pein-Hackelbusch I. Immohr U. Schedler T. Thiele S. Stübinger B. v. Rechenberg J. Waser-Althaus F. Schlottig M. Merli H. Dawe M. Karpíšek R. Wyrwa M. Schnabelrauch L. Meinel |
| author_sort | J. Ritzer |
| collection | DOAJ |
| description | Early detection of gum inflammation caused by dental implants helps prevent tissue damage. Here, the authors present a peptide sensor that generates a bitter taste when cleaved by proteases present in peri-implant disease, embed it in a chewing gum, and compare the probe to existing sensors using patient saliva. |
| first_indexed | 2024-12-14T15:09:53Z |
| format | Article |
| id | doaj.art-7363f6d5b83d47719736cb18a71ea473 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T15:09:53Z |
| publishDate | 2017-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-7363f6d5b83d47719736cb18a71ea4732022-12-21T22:56:35ZengNature PortfolioNature Communications2041-17232017-08-01811810.1038/s41467-017-00340-xDiagnosing peri-implant disease using the tongue as a 24/7 detectorJ. Ritzer0T. Lühmann1C. Rode2M. Pein-Hackelbusch3I. Immohr4U. Schedler5T. Thiele6S. Stübinger7B. v. Rechenberg8J. Waser-Althaus9F. Schlottig10M. Merli11H. Dawe12M. Karpíšek13R. Wyrwa14M. Schnabelrauch15L. Meinel16Institute for Pharmacy and Food Chemistry, Universität Würzburg, Am HublandInstitute for Pharmacy and Food Chemistry, Universität Würzburg, Am HublandBiomaterials Department, Innovent e.V.Institute for Pharmaceutics, Universität DüsseldorfInstitute for Pharmaceutics, Universität DüsseldorfPolyAn GmbHPolyAn GmbHMusculoskeletal Research Unit, Center for Applied Biotechnology and Molecular Medicine, Universität ZürichMusculoskeletal Research Unit, Center for Applied Biotechnology and Molecular Medicine, Universität ZürichThommen Medical AGThommen Medical AGIndent—International Dental Research and Education srlIndent—International Dental Research and Education srlBioVendor—Laboratorni medicina AS and Department of Human Pharmacology and Toxicology, University of Veterinary and Pharmaceutical SciencesBiomaterials Department, Innovent e.V.Biomaterials Department, Innovent e.V.Institute for Pharmacy and Food Chemistry, Universität Würzburg, Am HublandEarly detection of gum inflammation caused by dental implants helps prevent tissue damage. Here, the authors present a peptide sensor that generates a bitter taste when cleaved by proteases present in peri-implant disease, embed it in a chewing gum, and compare the probe to existing sensors using patient saliva.https://doi.org/10.1038/s41467-017-00340-x |
| spellingShingle | J. Ritzer T. Lühmann C. Rode M. Pein-Hackelbusch I. Immohr U. Schedler T. Thiele S. Stübinger B. v. Rechenberg J. Waser-Althaus F. Schlottig M. Merli H. Dawe M. Karpíšek R. Wyrwa M. Schnabelrauch L. Meinel Diagnosing peri-implant disease using the tongue as a 24/7 detector Nature Communications |
| title | Diagnosing peri-implant disease using the tongue as a 24/7 detector |
| title_full | Diagnosing peri-implant disease using the tongue as a 24/7 detector |
| title_fullStr | Diagnosing peri-implant disease using the tongue as a 24/7 detector |
| title_full_unstemmed | Diagnosing peri-implant disease using the tongue as a 24/7 detector |
| title_short | Diagnosing peri-implant disease using the tongue as a 24/7 detector |
| title_sort | diagnosing peri implant disease using the tongue as a 24 7 detector |
| url | https://doi.org/10.1038/s41467-017-00340-x |
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