Low-intensity focused ultrasound targeted microbubble destruction reduces tumor blood supply and sensitizes anti-PD-L1 immunotherapy

Low-intensity focused ultrasound targeted microbubble destruction reduces tumor blood supply and sensitizes anti-PD-L1 immunotherapy

Immune checkpoint blockade (ICB) typified by anti-PD-1/PD-L1 antibodies as a revolutionary treatment for solid malignancies has been limited to a subset of patients due to poor immunogenicity and inadequate T cell infiltration. Unfortunately, no effective strategies combined with ICB therapy are ava...

Full description

Bibliographic Details
Main Authors: Nianhong Wu, Yuting Cao, Ying Liu, Ying Zhou, Hongye He, Rui Tang, Li Wan, Can Wang, Xialin Xiong, Linhong Zhong, Pan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
immune checkpoint blockade
immune infiltration
antivascular therapy
cavitation
microbubble
low-intensity focused ultrasound
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1173381/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1173381/full

Similar Items