The association of α4β7 expression with HIV acquisition and disease progression in people who inject drugs and men who have sex with men: Case control studies

The association of α4β7 expression with HIV acquisition and disease progression in people who inject drugs and men who have sex with men: Case control studies

Background: α4β7 is a gut-homing integrin heterodimer that can act as a non-essential binding molecule for HIV. A previous study in heterosexual African women found that individuals with higher proportions of α4β7 expressing CD4+ T cells were more likely to become infected with HIV, as well as prese...

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Bibliographic Details
Main Authors: Alyssa R. Martin, Eshan U. Patel, Charles Kirby, Jacquie Astemborski, Gregory D. Kirk, Shruti H. Mehta, Kyle Marshall, Holly Janes, Ashley Clayton, Lawrence Corey, Scott M. Hammer, Magdalena E. Sobieszczyk, James Arthos, Claudia Cicala, Andrew D. Redd, Thomas C. Quinn
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304783

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