New Tripeptide Derivatives Asterripeptides A–C from Vietnamese Mangrove-Derived Fungus <em>Aspergillus terreus</em> LM.5.2
Three new tripeptide derivatives asterripeptides A–C (<b>1</b>–<b>3</b>) were isolated from Vietnamese mangrove-derived fungus <i>Aspergillus terreus</i> LM.5.2. Structures of isolated compounds were determined by a combination of NMR and ESIMS techniques. The abs...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/20/1/77 |
| Summary: | Three new tripeptide derivatives asterripeptides A–C (<b>1</b>–<b>3</b>) were isolated from Vietnamese mangrove-derived fungus <i>Aspergillus terreus</i> LM.5.2. Structures of isolated compounds were determined by a combination of NMR and ESIMS techniques. The absolute configurations of all stereocenters were determined using the Murfey’s method. The isolated compounds <b>1</b>–<b>3</b> contain a rare fungi cinnamic acid residue. The cytotoxicity of isolated compounds against several cancer cell lines and inhibition ability of sortase A from <i>Staphylococcus aureus</i> of asterripeptides A–C were investigated. |
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| ISSN: | 1660-3397 |