Head and neck cancer patients show poor oral health as compared to those with other types of cancer
Abstract Purpose Several studies have found associations between periodontitis and various types of cancer. Since the site of head and neck cancer (HNC) has contiguity or proximity to the oral cavity, it may be particularly influenced by oral inflammation. This study aimed to determine whether HNC p...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-09-01
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| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12903-023-03356-6 |
| _version_ | 1797451273610461184 |
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| author | Hiromi Nishi Taiji Obayashi Tsutomu Ueda Kouji Ohta Hideo Shigeishi Syuichi Munenaga Takashi Kono Yukio Yoshioka Masaru Konishi Ryotaro Taga Yuya Toigawa Takako Naruse Eri Ishida Eri Tsuboi Kanae Oda Kana Dainobu Tomoko Tokikazu Kotaro Tanimoto Naoya Kakimoto Hiroki Ohge Hidemi Kurihara Hiroyuki Kawaguchi |
| author_facet | Hiromi Nishi Taiji Obayashi Tsutomu Ueda Kouji Ohta Hideo Shigeishi Syuichi Munenaga Takashi Kono Yukio Yoshioka Masaru Konishi Ryotaro Taga Yuya Toigawa Takako Naruse Eri Ishida Eri Tsuboi Kanae Oda Kana Dainobu Tomoko Tokikazu Kotaro Tanimoto Naoya Kakimoto Hiroki Ohge Hidemi Kurihara Hiroyuki Kawaguchi |
| author_sort | Hiromi Nishi |
| collection | DOAJ |
| description | Abstract Purpose Several studies have found associations between periodontitis and various types of cancer. Since the site of head and neck cancer (HNC) has contiguity or proximity to the oral cavity, it may be particularly influenced by oral inflammation. This study aimed to determine whether HNC patients have poor oral health as compared to those with other types of cancer. Methods This study retrospectively examined oral environmental factors including periodontal inflamed surface area (PISA), a new periodontal inflammatory parameter. A total of 1030 cancer patients were divided into the HNC (n = 142) and other cancer (n = 888) groups. Furthermore, the HNC group was divided into high (n = 71) and low (n = 71) PISA subgroups, and independent risk factors affecting a high PISA value were investigated. Results Multivariate logistic regression analysis showed that number of missing teeth (odds ratio 1.72, 95% CI 1.15–2.56, P < 0.01), PISA (odds ratio 1.06, 95% CI 1.03–1.06, P < 0.05), and oral bacterial count (odds ratio 1.02, 95% CI 1.01–1.03, P < 0.01) were independent factors related to HNC. In addition, multivariate logistic regression analysis indicated that current smoker (odds ratio 7.51, 95% CI 1.63–34.71, P < 0.01) and presence of untreated dental caries (odds ratio 3.33, 95% CI 1.23–9.00, P < 0.05) were independent risk factors affecting high PISA values in HNC patients. Conclusion HNC patients have higher levels of gingival inflammation and poor oral health as compared to patients with other types of cancer, indicating that prompt oral assessment and an effective oral hygiene management plan are needed at the time of HNC diagnosis. |
| first_indexed | 2024-03-09T14:52:20Z |
| format | Article |
| id | doaj.art-736b5e5d7def430cba482261ede5aad5 |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-03-09T14:52:20Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-736b5e5d7def430cba482261ede5aad52023-11-26T14:25:07ZengBMCBMC Oral Health1472-68312023-09-0123111110.1186/s12903-023-03356-6Head and neck cancer patients show poor oral health as compared to those with other types of cancerHiromi Nishi0Taiji Obayashi1Tsutomu Ueda2Kouji Ohta3Hideo Shigeishi4Syuichi Munenaga5Takashi Kono6Yukio Yoshioka7Masaru Konishi8Ryotaro Taga9Yuya Toigawa10Takako Naruse11Eri Ishida12Eri Tsuboi13Kanae Oda14Kana Dainobu15Tomoko Tokikazu16Kotaro Tanimoto17Naoya Kakimoto18Hiroki Ohge19Hidemi Kurihara20Hiroyuki Kawaguchi21Department of General Dentistry, Hiroshima University HospitalDepartment of Dental Hygiene, Ogaki Women’s CollegeDepartment of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Public Oral Health, Program of Oral Health Sciences, Hiroshima UniversityDepartment of Public Oral Health, Program of Oral Health Sciences, Hiroshima UniversityDepartment of General Dentistry, Hiroshima University HospitalDepartment of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Oral and Maxillofacial Radiology, Hiroshima University HospitalDepartment of Program of Dentistry, School of Dentistry, Hiroshima UniversityDepartment of Program of Dentistry, School of Dentistry, Hiroshima UniversityDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Clinical Practice and Support, Hiroshima University HospitalDepartment of Clinical Practice and Support, Hiroshima University HospitalDepartment of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Oral and Maxillofacial Radiology, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityDepartment of Infectious Diseases, Hiroshima University HospitalDepartment of Periodontal Medicine, Division of Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima UniversityDepartment of General Dentistry, Hiroshima University HospitalAbstract Purpose Several studies have found associations between periodontitis and various types of cancer. Since the site of head and neck cancer (HNC) has contiguity or proximity to the oral cavity, it may be particularly influenced by oral inflammation. This study aimed to determine whether HNC patients have poor oral health as compared to those with other types of cancer. Methods This study retrospectively examined oral environmental factors including periodontal inflamed surface area (PISA), a new periodontal inflammatory parameter. A total of 1030 cancer patients were divided into the HNC (n = 142) and other cancer (n = 888) groups. Furthermore, the HNC group was divided into high (n = 71) and low (n = 71) PISA subgroups, and independent risk factors affecting a high PISA value were investigated. Results Multivariate logistic regression analysis showed that number of missing teeth (odds ratio 1.72, 95% CI 1.15–2.56, P < 0.01), PISA (odds ratio 1.06, 95% CI 1.03–1.06, P < 0.05), and oral bacterial count (odds ratio 1.02, 95% CI 1.01–1.03, P < 0.01) were independent factors related to HNC. In addition, multivariate logistic regression analysis indicated that current smoker (odds ratio 7.51, 95% CI 1.63–34.71, P < 0.01) and presence of untreated dental caries (odds ratio 3.33, 95% CI 1.23–9.00, P < 0.05) were independent risk factors affecting high PISA values in HNC patients. Conclusion HNC patients have higher levels of gingival inflammation and poor oral health as compared to patients with other types of cancer, indicating that prompt oral assessment and an effective oral hygiene management plan are needed at the time of HNC diagnosis.https://doi.org/10.1186/s12903-023-03356-6Head and neck cancerPeriodontal inflamed surface area |
| spellingShingle | Hiromi Nishi Taiji Obayashi Tsutomu Ueda Kouji Ohta Hideo Shigeishi Syuichi Munenaga Takashi Kono Yukio Yoshioka Masaru Konishi Ryotaro Taga Yuya Toigawa Takako Naruse Eri Ishida Eri Tsuboi Kanae Oda Kana Dainobu Tomoko Tokikazu Kotaro Tanimoto Naoya Kakimoto Hiroki Ohge Hidemi Kurihara Hiroyuki Kawaguchi Head and neck cancer patients show poor oral health as compared to those with other types of cancer BMC Oral Health Head and neck cancer Periodontal inflamed surface area |
| title | Head and neck cancer patients show poor oral health as compared to those with other types of cancer |
| title_full | Head and neck cancer patients show poor oral health as compared to those with other types of cancer |
| title_fullStr | Head and neck cancer patients show poor oral health as compared to those with other types of cancer |
| title_full_unstemmed | Head and neck cancer patients show poor oral health as compared to those with other types of cancer |
| title_short | Head and neck cancer patients show poor oral health as compared to those with other types of cancer |
| title_sort | head and neck cancer patients show poor oral health as compared to those with other types of cancer |
| topic | Head and neck cancer Periodontal inflamed surface area |
| url | https://doi.org/10.1186/s12903-023-03356-6 |
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