High Expression of ENO1 and Low Levels of Circulating Anti-ENO1 Autoantibodies in Patients with Myelodysplastic Neoplasms and Acute Myeloid Leukaemia

High Expression of ENO1 and Low Levels of Circulating Anti-ENO1 Autoantibodies in Patients with Myelodysplastic Neoplasms and Acute Myeloid Leukaemia

In solid tumours, high expression of the glycolytic enzyme, α-enolase (ENO1), predicts for poor patient overall survival (OS), and circulating autoantibodies to ENO1 correlate positively with diagnosis and negatively with advanced disease. Although ENO1 is one of the most highly expressed genes in a...

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Bibliographic Details
Main Authors: Lisa F. Lincz, Danielle Z. Theron, Daniel L. Barry, Fiona E. Scorgie, Jonathan Sillar, Opelo Sefhore, Anoop K. Enjeti, Kathryn A. Skelding
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
alpha-enolase
ENO1
autoantibodies
acute myeloid leukaemia
myelodysplastic neoplasms
bone marrow
Online Access:https://www.mdpi.com/2072-6694/16/5/884

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https://www.mdpi.com/2072-6694/16/5/884

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