Invasiveness of Hepatocellular Carcinoma Cell Lines: Contribution of Membrane-Type 1 Matrix Metalloproteinase

Invasiveness of Hepatocellular Carcinoma Cell Lines: Contribution of Membrane-Type 1 Matrix Metalloproteinase

Intrahepatic metastasis is one of the malignant features of hepatocellular carcinoma (HCC). Matrix metalloproteoinases (MMPs) and urokinase-type plasminogen activator (u-PA)/plasmin, are known to be associated with the invasive properties of various types of tumor cells. In this study, we examined w...

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Bibliographic Details
Main Authors: Koji Murakami, Rieko Sakukawa, Takashi Ikeda, Tomokazu Matsuura, Satoshi Hasumura, Seishi Nagamori, Yuji Yamada, Ikuo Saiki
Format: Article
Language:English
Published: Elsevier 1999-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
hepatocellular carcinoma
invasion
intrahepatic metastasis
MT1-MMP
HGF
Online Access:http://www.sciencedirect.com/science/article/pii/S147655869980013X

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