B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV
Polvere et al. investigate B cell responses after SARS-CoV-2 vaccination in people living with HIV undergoing anti-retroviral therapy. Spike-specific humoral and B cell responses persist for at least six months although a reduced ACE2/RBD binding inhibition capacity and different memory B phenotypes...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2023-01-01
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Series: | Communications Medicine |
Online Access: | https://doi.org/10.1038/s43856-023-00245-5 |
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author | Jacopo Polvere Massimiliano Fabbiani Gabiria Pastore Ilaria Rancan Barbara Rossetti Miriam Durante Sara Zirpoli Enrico Morelli Elena Pettini Simone Lucchesi Fabio Fiorino Mario Tumbarello Annalisa Ciabattini Francesca Montagnani Donata Medaglini |
author_facet | Jacopo Polvere Massimiliano Fabbiani Gabiria Pastore Ilaria Rancan Barbara Rossetti Miriam Durante Sara Zirpoli Enrico Morelli Elena Pettini Simone Lucchesi Fabio Fiorino Mario Tumbarello Annalisa Ciabattini Francesca Montagnani Donata Medaglini |
author_sort | Jacopo Polvere |
collection | DOAJ |
description | Polvere et al. investigate B cell responses after SARS-CoV-2 vaccination in people living with HIV undergoing anti-retroviral therapy. Spike-specific humoral and B cell responses persist for at least six months although a reduced ACE2/RBD binding inhibition capacity and different memory B phenotypes are observed compared to healthy controls. |
first_indexed | 2024-04-10T17:16:13Z |
format | Article |
id | doaj.art-73720c84f14541f9b1f7b7ba2b913879 |
institution | Directory Open Access Journal |
issn | 2730-664X |
language | English |
last_indexed | 2024-04-10T17:16:13Z |
publishDate | 2023-01-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Communications Medicine |
spelling | doaj.art-73720c84f14541f9b1f7b7ba2b9138792023-02-05T12:22:04ZengNature PortfolioCommunications Medicine2730-664X2023-01-013111010.1038/s43856-023-00245-5B cell response after SARS-CoV-2 mRNA vaccination in people living with HIVJacopo Polvere0Massimiliano Fabbiani1Gabiria Pastore2Ilaria Rancan3Barbara Rossetti4Miriam Durante5Sara Zirpoli6Enrico Morelli7Elena Pettini8Simone Lucchesi9Fabio Fiorino10Mario Tumbarello11Annalisa Ciabattini12Francesca Montagnani13Donata Medaglini14Laboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaDepartment of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaDepartment of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of SienaDepartment of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of SienaDepartment of Medical Biotechnologies, University of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaDepartment of Medical Biotechnologies, University of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaDepartment of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaDepartment of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of SienaLaboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of SienaPolvere et al. investigate B cell responses after SARS-CoV-2 vaccination in people living with HIV undergoing anti-retroviral therapy. Spike-specific humoral and B cell responses persist for at least six months although a reduced ACE2/RBD binding inhibition capacity and different memory B phenotypes are observed compared to healthy controls.https://doi.org/10.1038/s43856-023-00245-5 |
spellingShingle | Jacopo Polvere Massimiliano Fabbiani Gabiria Pastore Ilaria Rancan Barbara Rossetti Miriam Durante Sara Zirpoli Enrico Morelli Elena Pettini Simone Lucchesi Fabio Fiorino Mario Tumbarello Annalisa Ciabattini Francesca Montagnani Donata Medaglini B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV Communications Medicine |
title | B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV |
title_full | B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV |
title_fullStr | B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV |
title_full_unstemmed | B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV |
title_short | B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV |
title_sort | b cell response after sars cov 2 mrna vaccination in people living with hiv |
url | https://doi.org/10.1038/s43856-023-00245-5 |
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