RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE
Prognosis in heart failure (HF) is poor and mortality widely ranges - 15-60% per year. Cardiac resynchronization therapy (CRT) is a therapeutic concept for patients who have NYHA III or IV class, LVEF ≤ 35%, left bundle branch block with wide QRS ≥ 120ms and ventricular dyssynchrony on optimal medic...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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University in Nis, Faculty of Medicine
2013-06-01
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| Series: | Acta Medica Medianae |
| Subjects: | |
| Online Access: | http://publisher.medfak.ni.ac.rs/2013-html/2-broj/Tomislav%20Kostic-Resynchronization.pdf |
| _version_ | 1818528039703674880 |
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| author | Tomislav Kostić Zoran Perišić Goran Koraćević Dragana Stanojević Dragan Milić Vladimir Mitov Milan Pavlović Sonja Šalinger Martinović Lazar Todorović Snežana Ćirić Zdravković Mladjan Golubović |
| author_facet | Tomislav Kostić Zoran Perišić Goran Koraćević Dragana Stanojević Dragan Milić Vladimir Mitov Milan Pavlović Sonja Šalinger Martinović Lazar Todorović Snežana Ćirić Zdravković Mladjan Golubović |
| author_sort | Tomislav Kostić |
| collection | DOAJ |
| description | Prognosis in heart failure (HF) is poor and mortality widely ranges - 15-60% per year. Cardiac resynchronization therapy (CRT) is a therapeutic concept for patients who have NYHA III or IV class, LVEF ≤ 35%, left bundle branch block with wide QRS ≥ 120ms and ventricular dyssynchrony on optimal medical therapy.
The aim of the study was to determine the effects of resynchronization therapy in patients with moderate to severe HF.
In our study, 140 patients with HF were treated with different modalities of therapy in the Clinical Centre Niš. The first group of patients received CRT, and the second, control group were HF patients without echo criteria for CRT. In the control group, 36 patients received an implantable cardioverter-defibrillator (ICD).
Results of the study showed that resynchronization therapy in patients with HF improves different parameters: clinical symptoms, echocardiographic parameters, decreases QRS duration, increases 6-minute walk test distance and decreases mortality rate.
The benefit of cardiac resynchronization therapy in combination with optimal medical therapy is proven to be beneficial in patients with HF and asynchrony. CRT improved clinical symptoms of heart failure and had influence on disease progression. |
| first_indexed | 2024-12-11T06:44:25Z |
| format | Article |
| id | doaj.art-73723d025e0347939067a07abed79ba8 |
| institution | Directory Open Access Journal |
| issn | 0365-4478 1821-2794 |
| language | English |
| last_indexed | 2024-12-11T06:44:25Z |
| publishDate | 2013-06-01 |
| publisher | University in Nis, Faculty of Medicine |
| record_format | Article |
| series | Acta Medica Medianae |
| spelling | doaj.art-73723d025e0347939067a07abed79ba82022-12-22T01:17:07ZengUniversity in Nis, Faculty of MedicineActa Medica Medianae0365-44781821-27942013-06-015221014RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURETomislav Kostić0Zoran Perišić1Goran Koraćević2Dragana Stanojević3Dragan Milić4Vladimir Mitov5Milan Pavlović6Sonja Šalinger Martinović7Lazar Todorović8Snežana Ćirić Zdravković9Mladjan Golubović10Clinic of Cardiology, Clinical Center Niš, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Vascular Surgery, Clinical Center Niš, SerbiaHealthcare Center Zaje č ar, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Cardiology, Clinical Center Niš, SerbiaClinic of Vascular Surgery, Clinical Center Niš, SerbiaPrognosis in heart failure (HF) is poor and mortality widely ranges - 15-60% per year. Cardiac resynchronization therapy (CRT) is a therapeutic concept for patients who have NYHA III or IV class, LVEF ≤ 35%, left bundle branch block with wide QRS ≥ 120ms and ventricular dyssynchrony on optimal medical therapy. The aim of the study was to determine the effects of resynchronization therapy in patients with moderate to severe HF. In our study, 140 patients with HF were treated with different modalities of therapy in the Clinical Centre Niš. The first group of patients received CRT, and the second, control group were HF patients without echo criteria for CRT. In the control group, 36 patients received an implantable cardioverter-defibrillator (ICD). Results of the study showed that resynchronization therapy in patients with HF improves different parameters: clinical symptoms, echocardiographic parameters, decreases QRS duration, increases 6-minute walk test distance and decreases mortality rate. The benefit of cardiac resynchronization therapy in combination with optimal medical therapy is proven to be beneficial in patients with HF and asynchrony. CRT improved clinical symptoms of heart failure and had influence on disease progression.http://publisher.medfak.ni.ac.rs/2013-html/2-broj/Tomislav%20Kostic-Resynchronization.pdfheart failureresynchronization therapymortality |
| spellingShingle | Tomislav Kostić Zoran Perišić Goran Koraćević Dragana Stanojević Dragan Milić Vladimir Mitov Milan Pavlović Sonja Šalinger Martinović Lazar Todorović Snežana Ćirić Zdravković Mladjan Golubović RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE Acta Medica Medianae heart failure resynchronization therapy mortality |
| title | RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE |
| title_full | RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE |
| title_fullStr | RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE |
| title_full_unstemmed | RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE |
| title_short | RESYNCHRONIZATION THERAPY IN PATIENTS WITH HEART FAILURE |
| title_sort | resynchronization therapy in patients with heart failure |
| topic | heart failure resynchronization therapy mortality |
| url | http://publisher.medfak.ni.ac.rs/2013-html/2-broj/Tomislav%20Kostic-Resynchronization.pdf |
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