GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia

<p class="Pa3">3-methyl-1,2,3,4-tetrahydroquinoline (<strong>1</strong>), 4-hydroxyisoquinoline (<strong>2</strong>), 4-(1E)-hydroxy-1-prophenyl)-2-methoxyphenol (<strong>3</strong>), 4-acetoxycinnamic acid (<strong>4</strong>), Songora...

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Main Authors: M. Dumaa, Ya. Gerelt-Od, S. Javzan, D. Otgonhkishig, Ts. Doncheva, G. Yordanova, S. Philipov, D. Selenge
Format: Article
Language:English
Published: Mongolian Academy of Sciences 2016-03-01
Series:Mongolian Journal of Chemistry
Subjects:
Online Access:http://www.mongoliajol.info/index.php/MJC/article/view/669
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author M. Dumaa
Ya. Gerelt-Od
S. Javzan
D. Otgonhkishig
Ts. Doncheva
G. Yordanova
S. Philipov
D. Selenge
author_facet M. Dumaa
Ya. Gerelt-Od
S. Javzan
D. Otgonhkishig
Ts. Doncheva
G. Yordanova
S. Philipov
D. Selenge
author_sort M. Dumaa
collection DOAJ
description <p class="Pa3">3-methyl-1,2,3,4-tetrahydroquinoline (<strong>1</strong>), 4-hydroxyisoquinoline (<strong>2</strong>), 4-(1E)-hydroxy-1-prophenyl)-2-methoxyphenol (<strong>3</strong>), 4-acetoxycinnamic acid (<strong>4</strong>), Songoramine (<strong>5</strong>), and Songorine (<strong>6</strong>) have been determined by GC-MS analysis from the crude alkaloid mixtures (G<sub>1</sub>) obtained from the aerial parts of <em>Lagochilus ilicifolius </em>Bge. grown in Mongolia and comparison of the measured data with those from the literature. The compounds <strong>1</strong>-<strong>6 </strong>are described for the first time from <em>L.ilicifolius</em>. From these 3-methyl-1,2,3,4-tetrahydroquinoline (<strong>1) </strong>was determined for the first time from natural plants.</p><p>In addition, the antibacterial activity of fractions and total alkaloids were evaluated against <em>Staphylococcus aurous</em>, <em>Bacillus subtilis</em>, <em>Bacillus cereus </em>and <em>Escherichia coli </em>strains, respectively. The growth inhibition zones against gram-positive <em>S.aureus</em>, <em>B.subtilis</em>, <em>B.cereus </em>and gram negative <em>E.coli</em>, strains were observed. Positive results were achieved on 500 μg/disc concentration, but lower results or no active on 100 μg/disc concentration were for the plant extracts, fractions and total alkaloids.</p><p>Mongolian Journal of Chemistry 16 (42), 2015, 39-43</p>
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spelling doaj.art-73737c437cea4721b4ace3007c4ca0b22022-12-21T23:21:28ZengMongolian Academy of SciencesMongolian Journal of Chemistry2226-67392414-00822016-03-01160394310.5564/mjc.v16i0.669625GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in MongoliaM. Dumaa0Ya. Gerelt-Od1S. Javzan2D. Otgonhkishig3Ts. Doncheva4G. Yordanova5S. Philipov6D. Selenge7Institute of Chemistry and Chemical Technology, MAS, Peace Ave., Ulaanbaatar 13330Institute of Chemistry and Chemical Technology, MAS, Peace Ave., Ulaanbaatar 13330Institute of Chemistry and Chemical Technology, MAS, Peace Ave., Ulaanbaatar 13330Mongolian State University of Agriculture, School of Biological Resources and Management, UlaanbaatarInstitute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad.G.Bonchev St., bl. 9, 1113 SofiaInstitute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad.G.Bonchev St., bl. 9, 1113 SofiaInstitute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad.G.Bonchev St., bl. 9, 1113 SofiaInstitute of Chemistry and Chemical Technology, MAS, Peace Ave., Ulaanbaatar 133<p class="Pa3">3-methyl-1,2,3,4-tetrahydroquinoline (<strong>1</strong>), 4-hydroxyisoquinoline (<strong>2</strong>), 4-(1E)-hydroxy-1-prophenyl)-2-methoxyphenol (<strong>3</strong>), 4-acetoxycinnamic acid (<strong>4</strong>), Songoramine (<strong>5</strong>), and Songorine (<strong>6</strong>) have been determined by GC-MS analysis from the crude alkaloid mixtures (G<sub>1</sub>) obtained from the aerial parts of <em>Lagochilus ilicifolius </em>Bge. grown in Mongolia and comparison of the measured data with those from the literature. The compounds <strong>1</strong>-<strong>6 </strong>are described for the first time from <em>L.ilicifolius</em>. From these 3-methyl-1,2,3,4-tetrahydroquinoline (<strong>1) </strong>was determined for the first time from natural plants.</p><p>In addition, the antibacterial activity of fractions and total alkaloids were evaluated against <em>Staphylococcus aurous</em>, <em>Bacillus subtilis</em>, <em>Bacillus cereus </em>and <em>Escherichia coli </em>strains, respectively. The growth inhibition zones against gram-positive <em>S.aureus</em>, <em>B.subtilis</em>, <em>B.cereus </em>and gram negative <em>E.coli</em>, strains were observed. Positive results were achieved on 500 μg/disc concentration, but lower results or no active on 100 μg/disc concentration were for the plant extracts, fractions and total alkaloids.</p><p>Mongolian Journal of Chemistry 16 (42), 2015, 39-43</p>http://www.mongoliajol.info/index.php/MJC/article/view/669Lagochilus ilicifolius Bge., alkaloids, bacterial strains, disc diffusion, GC-MS
spellingShingle M. Dumaa
Ya. Gerelt-Od
S. Javzan
D. Otgonhkishig
Ts. Doncheva
G. Yordanova
S. Philipov
D. Selenge
GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia
Mongolian Journal of Chemistry
Lagochilus ilicifolius Bge., alkaloids, bacterial strains, disc diffusion, GC-MS
title GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia
title_full GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia
title_fullStr GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia
title_full_unstemmed GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia
title_short GC-MS analysis and antibacterial activity of some fractions from Lagochilus ilicifolius Bge. grown in Mongolia
title_sort gc ms analysis and antibacterial activity of some fractions from lagochilus ilicifolius bge grown in mongolia
topic Lagochilus ilicifolius Bge., alkaloids, bacterial strains, disc diffusion, GC-MS
url http://www.mongoliajol.info/index.php/MJC/article/view/669
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