Short prolactin isoforms are expressed in photoreceptors of canine retinas undergoing retinal degeneration
Abstract Prolactin (PRL) hormone functions as a pleiotropic cytokine with a protective role in the retina. We recently identified by transcriptome profiling that PRL is one of the most highly upregulated mRNAs in the retinas of mutant rcd1 (PDE6B) and xlpra2 (RPGR) dogs at advanced stages of photore...
Main Authors: | Raghavi Sudharsan, Leonardo Murgiano, Hsin-Yao Tang, Timothy W. Olsen, Venkata R. M. Chavali, Gustavo D. Aguirre, William A. Beltran |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-80691-6 |
Similar Items
-
Photochemical Restoration of Light Sensitivity in the Degenerated Canine Retina
by: Sergei Nikonov, et al.
Published: (2022-12-01) -
Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.
by: Stefania Marsili, et al.
Published: (2015-01-01) -
Strong upregulation of inflammatory genes accompanies photoreceptor demise in canine models of retinal degeneration.
by: Tatyana Appelbaum, et al.
Published: (2017-01-01) -
Canine retina has a primate fovea-like bouquet of cone photoreceptors which is affected by inherited macular degenerations.
by: William A Beltran, et al.
Published: (2014-01-01) -
Neural and Müller glial adaptation of the retina to photoreceptor degeneration
by: Henri O Leinonen, et al.
Published: (2023-01-01)