Fatigue induces long-lasting detrimental changes in motor-skill learning
Fatigue due to physical exertion is a ubiquitous phenomenon in everyday life and especially common in a range of neurological diseases. While the effect of fatigue on limiting skill execution are well known, its influence on learning new skills is unclear. This is of particular interest as it is com...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2019-03-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/40578 |
| _version_ | 1811235898610679808 |
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| author | Meret Branscheidt Panagiotis Kassavetis Manuel Anaya Davis Rogers Han Debra Huang Martin A Lindquist Pablo Celnik |
| author_facet | Meret Branscheidt Panagiotis Kassavetis Manuel Anaya Davis Rogers Han Debra Huang Martin A Lindquist Pablo Celnik |
| author_sort | Meret Branscheidt |
| collection | DOAJ |
| description | Fatigue due to physical exertion is a ubiquitous phenomenon in everyday life and especially common in a range of neurological diseases. While the effect of fatigue on limiting skill execution are well known, its influence on learning new skills is unclear. This is of particular interest as it is common practice to train athletes, musicians or perform rehabilitation exercises up to and beyond a point of fatigue. In a series of experiments, we describe how muscle fatigue, defined as degradation of maximum force after exertion, impairs motor-skill learning beyond its effects on task execution. The negative effects on learning are evidenced by impaired task acquisition on subsequent practice days even in the absence of fatigue. Further, we found that this effect is in part mediated centrally and can be alleviated by altering motor cortex function. Thus, the common practice of training while, or beyond, fatigue levels should be carefully reconsidered, since this affects overall long-term skill learning. |
| first_indexed | 2024-04-12T12:00:25Z |
| format | Article |
| id | doaj.art-73753cc687a04156b428fbe2e7ba1bcb |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T12:00:25Z |
| publishDate | 2019-03-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-73753cc687a04156b428fbe2e7ba1bcb2022-12-22T03:33:53ZengeLife Sciences Publications LtdeLife2050-084X2019-03-01810.7554/eLife.40578Fatigue induces long-lasting detrimental changes in motor-skill learningMeret Branscheidt0https://orcid.org/0000-0002-4008-6916Panagiotis Kassavetis1Manuel Anaya2Davis Rogers3Han Debra Huang4Martin A Lindquist5Pablo Celnik6The Human Brain Physiology and Stimulation Laboratory, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland; Clinical Neuroscience Center, University Hospital Zurich, Zurich, SwitzerlandThe Human Brain Physiology and Stimulation Laboratory, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom; Neurology Department, Boston University, Boston, MassachusettsThe Human Brain Physiology and Stimulation Laboratory, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MarylandThe Human Brain Physiology and Stimulation Laboratory, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland; The Johns Hopkins University School of Medicine, Baltimore, MarylandThe Human Brain Physiology and Stimulation Laboratory, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MarylandDepartment of Biostatistics, Johns Hopkins University, Baltimore, MarylandThe Human Brain Physiology and Stimulation Laboratory, Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MarylandFatigue due to physical exertion is a ubiquitous phenomenon in everyday life and especially common in a range of neurological diseases. While the effect of fatigue on limiting skill execution are well known, its influence on learning new skills is unclear. This is of particular interest as it is common practice to train athletes, musicians or perform rehabilitation exercises up to and beyond a point of fatigue. In a series of experiments, we describe how muscle fatigue, defined as degradation of maximum force after exertion, impairs motor-skill learning beyond its effects on task execution. The negative effects on learning are evidenced by impaired task acquisition on subsequent practice days even in the absence of fatigue. Further, we found that this effect is in part mediated centrally and can be alleviated by altering motor cortex function. Thus, the common practice of training while, or beyond, fatigue levels should be carefully reconsidered, since this affects overall long-term skill learning.https://elifesciences.org/articles/40578motor learningfatiguerTMSskill learningperformance bias |
| spellingShingle | Meret Branscheidt Panagiotis Kassavetis Manuel Anaya Davis Rogers Han Debra Huang Martin A Lindquist Pablo Celnik Fatigue induces long-lasting detrimental changes in motor-skill learning eLife motor learning fatigue rTMS skill learning performance bias |
| title | Fatigue induces long-lasting detrimental changes in motor-skill learning |
| title_full | Fatigue induces long-lasting detrimental changes in motor-skill learning |
| title_fullStr | Fatigue induces long-lasting detrimental changes in motor-skill learning |
| title_full_unstemmed | Fatigue induces long-lasting detrimental changes in motor-skill learning |
| title_short | Fatigue induces long-lasting detrimental changes in motor-skill learning |
| title_sort | fatigue induces long lasting detrimental changes in motor skill learning |
| topic | motor learning fatigue rTMS skill learning performance bias |
| url | https://elifesciences.org/articles/40578 |
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