The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases
A two year follow-up of the first two volunteers vaccinated icith the live PF Trypanosoma cruzi strain demonstrated that the parasitological and clinical test were negative during and after that period. Of the serological tests employed, the CFT presented, in only one case, conflicting results, part...
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Format: | Article |
Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
1972-08-01
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Series: | Revista da Sociedade Brasileira de Medicina Tropical |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821972000400002&lng=en&tlng=en |
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author | Humberto Menezes |
author_facet | Humberto Menezes |
author_sort | Humberto Menezes |
collection | DOAJ |
description | A two year follow-up of the first two volunteers vaccinated icith the live PF Trypanosoma cruzi strain demonstrated that the parasitological and clinical test were negative during and after that period. Of the serological tests employed, the CFT presented, in only one case, conflicting results, particulary in one laboratory and among different laboratories. However negative results were greater than all doubtful and positive one combined. The IFT icere negative in both patients. Some comments are made about the sensibility and specificity of these tests. The author concluded that the vaccine, in spite of the very large dose used in these cases, seems to be safe for human beings. |
first_indexed | 2024-04-12T14:33:19Z |
format | Article |
id | doaj.art-737be09d489c449c9f2676683d1e127b |
institution | Directory Open Access Journal |
issn | 1678-9849 |
language | English |
last_indexed | 2024-04-12T14:33:19Z |
publishDate | 1972-08-01 |
publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
record_format | Article |
series | Revista da Sociedade Brasileira de Medicina Tropical |
spelling | doaj.art-737be09d489c449c9f2676683d1e127b2022-12-22T03:29:12ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98491972-08-016417718010.1590/S0037-86821972000400002S0037-86821972000400002The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two casesHumberto Menezes0Universidade de São PauloA two year follow-up of the first two volunteers vaccinated icith the live PF Trypanosoma cruzi strain demonstrated that the parasitological and clinical test were negative during and after that period. Of the serological tests employed, the CFT presented, in only one case, conflicting results, particulary in one laboratory and among different laboratories. However negative results were greater than all doubtful and positive one combined. The IFT icere negative in both patients. Some comments are made about the sensibility and specificity of these tests. The author concluded that the vaccine, in spite of the very large dose used in these cases, seems to be safe for human beings.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821972000400002&lng=en&tlng=en |
spellingShingle | Humberto Menezes The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases Revista da Sociedade Brasileira de Medicina Tropical |
title | The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases |
title_full | The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases |
title_fullStr | The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases |
title_full_unstemmed | The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases |
title_short | The vaccination of h uman beings with live avirulent vaccine of Trypanosoma cruzi: A two year follow-up of the first two cases |
title_sort | vaccination of h uman beings with live avirulent vaccine of trypanosoma cruzi a two year follow up of the first two cases |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821972000400002&lng=en&tlng=en |
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