cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors

Bibliographic Details
Main Authors: Byeongkwi Min, Jonghwa Jin, Hyeree Kim, Nam-Gu Her, Changsik Park, Donggeon Kim, Jehoon Yang, Juhyeon Hwang, Eunmi Kim, Minji Choi, Ho Young Song, Do-Hyun Nam, Yeup Yoon
Format: Article
Language:English
Published: American Chemical Society 2020-09-01
Series:ACS Omega
Online Access:http://dx.doi.org/10.1021/acsomega.0c03102
_version_ 1818551944575188992
author Byeongkwi Min
Jonghwa Jin
Hyeree Kim
Nam-Gu Her
Changsik Park
Donggeon Kim
Jehoon Yang
Juhyeon Hwang
Eunmi Kim
Minji Choi
Ho Young Song
Do-Hyun Nam
Yeup Yoon
author_facet Byeongkwi Min
Jonghwa Jin
Hyeree Kim
Nam-Gu Her
Changsik Park
Donggeon Kim
Jehoon Yang
Juhyeon Hwang
Eunmi Kim
Minji Choi
Ho Young Song
Do-Hyun Nam
Yeup Yoon
author_sort Byeongkwi Min
collection DOAJ
first_indexed 2024-12-12T09:06:38Z
format Article
id doaj.art-7381e342312845459ff1c0b984914dcc
institution Directory Open Access Journal
issn 2470-1343
language English
last_indexed 2024-12-12T09:06:38Z
publishDate 2020-09-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj.art-7381e342312845459ff1c0b984914dcc2022-12-22T00:29:39ZengAmerican Chemical SocietyACS Omega2470-13432020-09-01540257982580910.1021/acsomega.0c03102cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression TumorsByeongkwi Min0Jonghwa Jin1Hyeree Kim2Nam-Gu Her3Changsik Park4Donggeon Kim5Jehoon Yang6Juhyeon Hwang7Eunmi Kim8Minji Choi9Ho Young Song10Do-Hyun Nam11Yeup Yoon12Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of KoreaDepartment of Convergence Technical Support, New Drug Development Center, Cheongju-si, Chungbuk, KoreaDepartment of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of KoreaInstitute for Refractory Cancer Research, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Republic of KoreaLegoChem Biosciences, Inc., Daejeon, Republic of KoreaInstitute for Refractory Cancer Research, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Republic of KoreaAnimal Research and Molecular Imaging Center, Samsung Biomedical Research Institute, Seoul, Republic of KoreaInstitute for Refractory Cancer Research, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Republic of KoreaInstitute for Refractory Cancer Research, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Republic of KoreaLegoChem Biosciences, Inc., Daejeon, Republic of KoreaLegoChem Biosciences, Inc., Daejeon, Republic of KoreaDepartment of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of KoreaDepartment of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Koreahttp://dx.doi.org/10.1021/acsomega.0c03102
spellingShingle Byeongkwi Min
Jonghwa Jin
Hyeree Kim
Nam-Gu Her
Changsik Park
Donggeon Kim
Jehoon Yang
Juhyeon Hwang
Eunmi Kim
Minji Choi
Ho Young Song
Do-Hyun Nam
Yeup Yoon
cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors
ACS Omega
title cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors
title_full cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors
title_fullStr cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors
title_full_unstemmed cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors
title_short cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors
title_sort circr201 dpbd a novel pyrrolobenzodiazepine dimer containing site specific antibody drug conjugate targeting c met overexpression tumors
url http://dx.doi.org/10.1021/acsomega.0c03102
work_keys_str_mv AT byeongkwimin circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT jonghwajin circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT hyereekim circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT namguher circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT changsikpark circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT donggeonkim circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT jehoonyang circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT juhyeonhwang circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT eunmikim circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT minjichoi circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT hoyoungsong circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT dohyunnam circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors
AT yeupyoon circr201dpbdanovelpyrrolobenzodiazepinedimercontainingsitespecificantibodydrugconjugatetargetingcmetoverexpressiontumors