Novel Thiophene Thioglycosides Substituted with the Benzothiazole Moiety: Synthesis, Characterization, Antiviral and Anticancer Evaluations, and NS3/4A and USP7 Enzyme Inhibitions

Novel Thiophene Thioglycosides Substituted with the Benzothiazole Moiety: Synthesis, Characterization, Antiviral and Anticancer Evaluations, and NS3/4A and USP7 Enzyme Inhibitions

Bibliographic Details
Main Authors:	Rasha A. Azzam, Nagwa M. Gad, Galal H. Elgemeie
Format:	Article
Language:	English
Published:	American Chemical Society 2022-09-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.2c03444

Similar Items

Novel Synthesis and Antiviral Evaluation of New Benzothiazole-Bearing N‑Sulfonamide 2‑Pyridone Derivatives as USP7 Enzyme Inhibitors
by: Rasha A. Azzam, et al.
Published: (2020-11-01)

Novel thiophene derivatives with sulfonamide, isoxazole, benzothiazole, quinoline and anthracene moieties as potential anticancer agents
by: Ghorab Mostafa M., et al.
Published: (2014-12-01)

Sofosbuvir Thio-analogues: Synthesis and Antiviral Evaluation of the First Novel Pyridine- and Pyrimidine-Based Thioglycoside Phosphoramidates
by: Mamdouh Attia Abu-Zaied, et al.
Published: (2020-06-01)

4-Amino-5-(4-bromobenzoyl)-3-(benzo[d]thiazol-2-yl)-2-[(2′,3′,4′,6′-tetra-O-acetyl-β-d-galactopyranosyl)sulfanyl]thiophene
by: Rasha A. Azzam, et al.
Published: (2022-04-01)

Synthesis, Physicochemical Properties and Molecular Docking of New Benzothiazole Derivatives as Antimicrobial Agents Targeting DHPS Enzyme
by: Rasha A. Azzam, et al.
Published: (2022-12-01)

Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV‑2 and Avian Influenza H5N1 Viruses
by: Mamdouh A. Abu-Zaied, et al.
Published: (2021-06-01)

Design and Synthesis of a New Class of Pyridine-Based N‑Sulfonamides Exhibiting Antiviral, Antimicrobial, and Enzyme Inhibition Characteristics
by: Rasha A. Azzam, et al.
Published: (2020-09-01)

Toward Developing Therapies against Corona Virus: Synthesis and Anti-Avian Influenza Virus Activity of Novel Cytosine Thioglycoside Analogues
by: Mamdouh A. Abu-Zaied, et al.
Published: (2020-08-01)

Evaluation of the biological potencies of newly synthesized berberine derivatives bearing benzothiazole moieties with substituted functionalities
by: Bhupendra Mistry, et al.
Published: (2017-02-01)

Crystal structure of 2-(benzo[d]thiazol-2-yl)-3,3-bis(ethylsulfanyl)acrylonitrile
by: Rasha A. Azzam, et al.
Published: (2022-04-01)

Novel Uridine Glycoconjugates, Derivatives of 4-Aminophenyl 1-Thioglycosides, as Potential Antiviral Compounds
by: Ewelina Krol, et al.
Published: (2018-06-01)

Novel purine thioglycoside analogs: synthesis, nanoformulation and biological evaluation in in vitro human liver and breast cancer models
by: Abu-Zaied MA, et al.
Published: (2019-07-01)

Synthesis of some new hydrazone derivatives containing benzothiazole moiety
by: Özdemir Ahmet, et al.
Published: (2012-01-01)

Novel Purine Thioglycoside Analogs: Synthesis, Nanoformulation and Biological Evaluation in in vitro Human Liver and Breast Cancer Models [Retraction]
by: Abu-Zaied MA, et al.
Published: (2022-07-01)

Green synthesis and crystal structure of 3-(benzothiazol-2-yl)thiophene
by: Linh Nguyen Ngoc, et al.
Published: (2017-11-01)

Activation of Thioglycosides with Copper(II) Bromide
by: Faranak Pooladian, et al.
Published: (2022-10-01)

Design, Synthesis, and Antimicrobial Evaluation of a New Series of N‑Sulfonamide 2‑Pyridones as Dual Inhibitors of DHPS and DHFR Enzymes
by: Rasha A. Azzam, et al.
Published: (2020-04-01)

Synthesis and insecticidal activity of novel benzothiazole derivatives containing the coumarin moiety
by: Wei-Jie Si, et al.
Published: (2018-09-01)

Synthesis and Evaluation of Antimicrobial activity of several new Maleimides to Benzothiazole moiety
by: Baghdad Science Journal
Published: (2013-09-01)

N-[(E)-Thiophen-2-ylmethylidene]-1,3-benzothiazol-2-amine
by: Irvin N. Booysen, et al.
Published: (2012-08-01)

Investigations on the Anticancer Potential of Benzothiazole-Based Metallacycles
by: Stephan Mokesch, et al.
Published: (2020-04-01)

Cytotoxic Gold(I) Complexes with Amidophosphine Ligands Containing Thiophene Moieties
by: Helen Goitia, et al.
Published: (2019-01-01)

Synthesis and anticancer evaluation of 2-phenyl thiaolidinone substituted 2-phenyl benzothiazole-6-carboxylic acid derivatives
by: Padmavathi P. Prabhu, et al.
Published: (2015-03-01)

Synthesis and Biological Activity of Substituted Benzothiazole Derivatives
by: Karminski-Zamola, G., et al.
Published: (2008-06-01)

Synthesis and antitumor evaluation of thiophene based azo dyes incorporating pyrazolone moiety
by: Moustafa A. Gouda, et al.
Published: (2016-03-01)

Synthesis of protected precursors of chitin oligosaccharides by electrochemical polyglycosylation of thioglycosides
by: Md Azadur Rahman, et al.
Published: (2022-08-01)

Synthesis, characterization and comparative study the microbial activity of some heterocyclic compounds containing oxazole and benzothiazole moieties
by: Ivan H.R. Tomi, et al.
Published: (2015-07-01)

Synthesis carbonic anhydrase enzyme inhibition and antioxidant activity of novel benzothiazole derivatives incorporating glycine, methionine, alanine, and phenylalanine moieties
by: Deniz Üzeroğlu Payaz, et al.
Published: (2019-01-01)

2-Anilino-4-(1,3-benzothiazol-2-yl)-5-(4-chlorobenzoyl)thiophene-3-carbonitrile
by: Hoong-Kun Fun, et al.
Published: (2012-08-01)

Crystal structures of three homologues with increasing ring size: 2-methoxy-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile, 2-methoxy-4-(thiophen-2-yl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile and 2-methoxy-4-(thiophen-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile
by: Ali M. S. Hebishy, et al.
Published: (2023-04-01)

Synthesis and Anticancer Activity of New 1-Thia-4-azaspiro[4.5]decane, Their Derived Thiazolopyrimidine and 1,3,4-Thiadiazole Thioglycosides
by: Eman M. Flefel, et al.
Published: (2017-01-01)

Crystal structure of N-[6-amino-5-(benzo[d]thiazol-2-yl)-3-cyano-4-methylsulfanyl-2-oxo-1,2-dihydropyridin-1-yl]-4-methylbenzenesulfonamide dimethylformamide monosolvate
by: Rasha A. Azzam, et al.
Published: (2017-12-01)

Crystal structure of N′-[2-(benzo[d]thiazol-2-yl)acetyl]-4-methylbenzenesulfonohydrazide
by: Rasha A. Azzam, et al.
Published: (2017-07-01)

Benzothiazole and Chromone Derivatives as Potential ATR Kinase Inhibitors and Anticancer Agents
by: Mykhaylo Frasinyuk, et al.
Published: (2022-07-01)

Synthetic Approaches to Biologically Active C-2-Substituted Benzothiazoles
by: Bagrat A. Shainyan, et al.
Published: (2022-04-01)

Synthesis and study of new antimicrobial benzothiazoles substituted on heterocyclic ring
by: Ivica Sigmundová, et al.
Published: (2008-04-01)

Design and synthesis of Quinazolinone, Benzothiazole derivatives bearing guanidinopropanoic acid moiety and their Schiff bases as cytotoxic and antimicrobial agents
by: Palani Venkatesh, et al.
Published: (2016-09-01)

Synthesis of purin 2'-deoxynucleoside analogues by using thioglycosides: 2',3'-dideoxyguanosine
by: G. D. Gungarova, et al.
Published: (2006-02-01)

Design, synthesis and antimicrobial evaluation of thioglycosides of a novel class of 2-mercaptonicotinonitriles
by: Amira Atef Ghoneim, et al.
Published: (2020-12-01)

Urea–hydrogen peroxide prompted the selective and controlled oxidation of thioglycosides into sulfoxides and sulfones
by: Adesh Kumar Singh, et al.
Published: (2017-06-01)