Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate
The present study was carried out to investigate the influence of Sempervivum tectorum aqueous extract and melatonin on reduced glutathione (GSH) protective effect in Wistar albino rat blood exposed to aluminium sulphate- Al2(SO4)3. The rats were divided in one control group (C) and 7 experimental g...
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| Format: | Article |
| Language: | English |
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Agroprint Timisoara
2023-09-01
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| Series: | Scientific Papers Animal Science and Biotechnologies |
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| Online Access: | https://spasb.ro/index.php/public_html/article/view/529 |
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| author | Corina Gravila Florin Muselin Camelia Tulcan Mirela Ahmadi – Khoie Ariana- Bianca Velciov Georgeta- Sofia Pintilie |
| author_facet | Corina Gravila Florin Muselin Camelia Tulcan Mirela Ahmadi – Khoie Ariana- Bianca Velciov Georgeta- Sofia Pintilie |
| author_sort | Corina Gravila |
| collection | DOAJ |
| description | The present study was carried out to investigate the influence of Sempervivum tectorum aqueous extract and melatonin on reduced glutathione (GSH) protective effect in Wistar albino rat blood exposed to aluminium sulphate- Al2(SO4)3. The rats were divided in one control group (C) and 7 experimental groups (E). The control group received tap water. The experimental rats were feed the following way: E1 group – aluminum sulphate, daily, for 3 months; : E2 group – Sempervivum tectorum, daily, for 3 months; : E3 group – melatonin, daily, for 3 months; : E4 group – aluminum sulphate with Sempervivum tectorum, daily, for 3 months; : E5 group – aluminum sulphate with melatonin, daily, for 3 months; E6 group – aluminum sulphate, daily, for 3 months, and thereafter with Sempervivum tectorum for 1 month; E7 group – aluminum sulphate, daily, for 3 month, and thereafter with melatonin for 1 month. This study showed that Aluminum toxicity induced lower GSH. The oxidative stress caused by aluminum, given individual, is more pronounced than in the case in which aluminum is administered simultaneously with Sempervivum tectorum or melatonin. Decreasing GSH value is very small if Sempervivum tectorum or melatonin is given for one month, three months after the administration of aluminum. Effect induced by melatonin is more favorable than that of Sempervivum tectorum. |
| first_indexed | 2024-04-24T11:22:30Z |
| format | Article |
| id | doaj.art-7384d97b1a6d4562b9f87a986fea6eb6 |
| institution | Directory Open Access Journal |
| issn | 1841-9364 2344-4576 |
| language | English |
| last_indexed | 2024-04-24T11:22:30Z |
| publishDate | 2023-09-01 |
| publisher | Agroprint Timisoara |
| record_format | Article |
| series | Scientific Papers Animal Science and Biotechnologies |
| spelling | doaj.art-7384d97b1a6d4562b9f87a986fea6eb62024-04-11T04:29:15ZengAgroprint TimisoaraScientific Papers Animal Science and Biotechnologies1841-93642344-45762023-09-014719999529Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum SulphateCorina Gravila0Florin Muselin1Camelia Tulcan2Mirela Ahmadi – Khoie3Ariana- Bianca Velciov4Georgeta- Sofia Pintilie5Banat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Faculty of Animal Science and Biotechnologies, 300645, Timişoara, Calea Aradului 119, RomaniaBanat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Faculty of Veterinary Medicine, 300645, Timişoara, Calea Aradului 119, RomaniaBanat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Faculty of Veterinary Medicine, 300645, Timişoara, Calea Aradului 119, RomaniaBanat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Faculty of Veterinary Medicine, 300645, Timişoara, Calea Aradului 119, RomaniaBanat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Faculty of Agro-Food Processing Technologies,300645, Timişoara, Calea Aradului 119, RomaniaBanat´s University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Faculty of Agro-Food Processing Technologies,300645, Timişoara, Calea Aradului 119, RomaniaThe present study was carried out to investigate the influence of Sempervivum tectorum aqueous extract and melatonin on reduced glutathione (GSH) protective effect in Wistar albino rat blood exposed to aluminium sulphate- Al2(SO4)3. The rats were divided in one control group (C) and 7 experimental groups (E). The control group received tap water. The experimental rats were feed the following way: E1 group – aluminum sulphate, daily, for 3 months; : E2 group – Sempervivum tectorum, daily, for 3 months; : E3 group – melatonin, daily, for 3 months; : E4 group – aluminum sulphate with Sempervivum tectorum, daily, for 3 months; : E5 group – aluminum sulphate with melatonin, daily, for 3 months; E6 group – aluminum sulphate, daily, for 3 months, and thereafter with Sempervivum tectorum for 1 month; E7 group – aluminum sulphate, daily, for 3 month, and thereafter with melatonin for 1 month. This study showed that Aluminum toxicity induced lower GSH. The oxidative stress caused by aluminum, given individual, is more pronounced than in the case in which aluminum is administered simultaneously with Sempervivum tectorum or melatonin. Decreasing GSH value is very small if Sempervivum tectorum or melatonin is given for one month, three months after the administration of aluminum. Effect induced by melatonin is more favorable than that of Sempervivum tectorum.https://spasb.ro/index.php/public_html/article/view/529aluminumgshmelatoninratsempervivum tectorum |
| spellingShingle | Corina Gravila Florin Muselin Camelia Tulcan Mirela Ahmadi – Khoie Ariana- Bianca Velciov Georgeta- Sofia Pintilie Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate Scientific Papers Animal Science and Biotechnologies aluminum gsh melatonin rat sempervivum tectorum |
| title | Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate |
| title_full | Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate |
| title_fullStr | Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate |
| title_full_unstemmed | Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate |
| title_short | Study on the Influence of Sempervivum tectorum and Melatonin on Glutathion Protective Effects in Rats Blood Exposed to Aluminum Sulphate |
| title_sort | study on the influence of sempervivum tectorum and melatonin on glutathion protective effects in rats blood exposed to aluminum sulphate |
| topic | aluminum gsh melatonin rat sempervivum tectorum |
| url | https://spasb.ro/index.php/public_html/article/view/529 |
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