LASSO regression shows histidine and sphingosine 1 phosphate are linked to both sepsis mortality and endothelial damage

LASSO regression shows histidine and sphingosine 1 phosphate are linked to both sepsis mortality and endothelial damage

Abstract Sepsis is a major cause of death worldwide, with a mortality rate that has remained stubbornly high. The current gold standard of risk stratifying sepsis patients provides limited mechanistic insight for therapeutic targeting. An improved ability to predict sepsis mortality and to understan...

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Bibliographic Details
Main Authors: Pär I. Johansson, Hanne H. Henriksen, Sigurður T. Karvelsson, Óttar Rolfsson, Martin Schønemann-Lund, Morten H. Bestle, Sarah McGarrity
Format: Article
Language:English
Published: BMC 2024-01-01
Series:European Journal of Medical Research
Online Access:https://doi.org/10.1186/s40001-023-01612-7

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