Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity
Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems t...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2023-01-01
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| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100838&tlng=en |
| _version_ | 1797957095354531840 |
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| author | Roan Ngoc Anh Huy Ramu Govindan Navanita Sivaramakumar Rajesh Raman Saravanan Jayaraman Duraiswamy Basavan Dhanabal S Palanisamy |
| author_facet | Roan Ngoc Anh Huy Ramu Govindan Navanita Sivaramakumar Rajesh Raman Saravanan Jayaraman Duraiswamy Basavan Dhanabal S Palanisamy |
| author_sort | Roan Ngoc Anh Huy |
| collection | DOAJ |
| description | Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis. |
| first_indexed | 2024-04-10T23:58:59Z |
| format | Article |
| id | doaj.art-7391ff66170143799c76c2edb1003645 |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-04-10T23:58:59Z |
| publishDate | 2023-01-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-7391ff66170143799c76c2edb10036452023-01-10T07:35:16ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902023-01-015810.1590/s2175-97902022e20582Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activityRoan Ngoc Anh HuyRamu Govindanhttps://orcid.org/0000-0002-0572-9517Navanita SivaramakumarRajesh RamanSaravanan JayaramanDuraiswamy BasavanDhanabal S PalanisamyAbstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100838&tlng=enCalculiLitholyticBasella rubraPlant organs |
| spellingShingle | Roan Ngoc Anh Huy Ramu Govindan Navanita Sivaramakumar Rajesh Raman Saravanan Jayaraman Duraiswamy Basavan Dhanabal S Palanisamy Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity Brazilian Journal of Pharmaceutical Sciences Calculi Litholytic Basella rubra Plant organs |
| title | Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_full | Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_fullStr | Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_full_unstemmed | Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_short | Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity |
| title_sort | inhibition of calculi forming oxalate by dietary basella rubra organs litholytic activity |
| topic | Calculi Litholytic Basella rubra Plant organs |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100838&tlng=en |
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