Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery
Background: Nowadays, video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS) are known to be safe and efficient surgical procedures to treat early-stage non-small cell lung cancer (NSCLC). We assessed whether RATS increased disease-free survival (DFS) compared...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/11/2611 |
| _version_ | 1797493979045953536 |
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| author | François Montagne Zied Chaari Benjamin Bottet Matthieu Sarsam Frankie Mbadinga Jean Selim Florian Guisier André Gillibert Jean-Marc Baste |
| author_facet | François Montagne Zied Chaari Benjamin Bottet Matthieu Sarsam Frankie Mbadinga Jean Selim Florian Guisier André Gillibert Jean-Marc Baste |
| author_sort | François Montagne |
| collection | DOAJ |
| description | Background: Nowadays, video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS) are known to be safe and efficient surgical procedures to treat early-stage non-small cell lung cancer (NSCLC). We assessed whether RATS increased disease-free survival (DFS) compared with VATS for lobectomy and segmentectomy. Methods: This retrospective cohort study included patients treated for resectable NSCLC performed by RATS or VATS, in our tertiary care center from 2012 to 2019. Patients’ data were prospectively recorded and reviewed in the French EPITHOR database. Primary outcomes were 5-year DFS for lobectomy and 3-year DFS for segmentectomy, compared by propensity-score adjusted difference of Kaplan–Meier estimates. Results: Among 844 lung resections, 436 VATS and 234 RATS lobectomies and 46 VATS and 128 RATS segmentectomies were performed. For lobectomy, the adjusted 5-year DFS was 60.9% (95% confidence interval (CI) 52.9–68.8%) for VATS and 52.7% (95%CI 41.7–63.7%) for RATS, with a difference estimated at −8.3% (−22.2–+4.9%, <i>p</i> = 0.24). For segmentectomy, the adjusted 3-year DFS was 84.6% (95%CI 69.8–99.0%) for VATS and 72.9% (95%CI 50.6–92.4%) for RATS, with a difference estimated at −11.7% (−38.7–+7.8%, <i>p</i> = 0.21). Conclusions: RATS failed to show its superiority over VATS for resectable NSCLC. |
| first_indexed | 2024-03-10T01:27:45Z |
| format | Article |
| id | doaj.art-739200d82d5c4f1896df62f9de2610ab |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T01:27:45Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-739200d82d5c4f1896df62f9de2610ab2023-11-23T13:48:12ZengMDPI AGCancers2072-66942022-05-011411261110.3390/cancers14112611Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted SurgeryFrançois Montagne0Zied Chaari1Benjamin Bottet2Matthieu Sarsam3Frankie Mbadinga4Jean Selim5Florian Guisier6André Gillibert7Jean-Marc Baste8Department of Thoracic Surgery, CHU Lille, F-59000 Lille, FranceDepartment of Thoracic and Cardiovascular Surgery, University of Sfax, Habib Bourguiba University Hospital, Sfax 3029, TunisiaDepartment of General and Thoracic Surgery, Rouen University Hospital, 1 Rue de Germont, F-76000 Rouen, FranceDepartment of General and Thoracic Surgery, Rouen University Hospital, 1 Rue de Germont, F-76000 Rouen, FranceDepartment of General and Thoracic Surgery, Rouen University Hospital, 1 Rue de Germont, F-76000 Rouen, FranceDepartment of Anesthesiology and Critical Care, CHU Rouen, F-76000 Rouen, FranceThoracic Oncology and Respiratory Intensive Care Unit, Department of Pneumology, Rouen University Hospital, F-76000 Rouen, FranceDepartment of Biostatistics, CHU Rouen, F-76000 Rouen, FranceDepartment of General and Thoracic Surgery, Rouen University Hospital, 1 Rue de Germont, F-76000 Rouen, FranceBackground: Nowadays, video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS) are known to be safe and efficient surgical procedures to treat early-stage non-small cell lung cancer (NSCLC). We assessed whether RATS increased disease-free survival (DFS) compared with VATS for lobectomy and segmentectomy. Methods: This retrospective cohort study included patients treated for resectable NSCLC performed by RATS or VATS, in our tertiary care center from 2012 to 2019. Patients’ data were prospectively recorded and reviewed in the French EPITHOR database. Primary outcomes were 5-year DFS for lobectomy and 3-year DFS for segmentectomy, compared by propensity-score adjusted difference of Kaplan–Meier estimates. Results: Among 844 lung resections, 436 VATS and 234 RATS lobectomies and 46 VATS and 128 RATS segmentectomies were performed. For lobectomy, the adjusted 5-year DFS was 60.9% (95% confidence interval (CI) 52.9–68.8%) for VATS and 52.7% (95%CI 41.7–63.7%) for RATS, with a difference estimated at −8.3% (−22.2–+4.9%, <i>p</i> = 0.24). For segmentectomy, the adjusted 3-year DFS was 84.6% (95%CI 69.8–99.0%) for VATS and 72.9% (95%CI 50.6–92.4%) for RATS, with a difference estimated at −11.7% (−38.7–+7.8%, <i>p</i> = 0.21). Conclusions: RATS failed to show its superiority over VATS for resectable NSCLC.https://www.mdpi.com/2072-6694/14/11/2611non-small cell lung cancerlong-term survivaldisease-free survivalminimally invasive surgeryVATSRATS |
| spellingShingle | François Montagne Zied Chaari Benjamin Bottet Matthieu Sarsam Frankie Mbadinga Jean Selim Florian Guisier André Gillibert Jean-Marc Baste Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery Cancers non-small cell lung cancer long-term survival disease-free survival minimally invasive surgery VATS RATS |
| title | Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery |
| title_full | Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery |
| title_fullStr | Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery |
| title_full_unstemmed | Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery |
| title_short | Long-Term Survival Following Minimally Invasive Lung Cancer Surgery: Comparing Robotic-Assisted and Video-Assisted Surgery |
| title_sort | long term survival following minimally invasive lung cancer surgery comparing robotic assisted and video assisted surgery |
| topic | non-small cell lung cancer long-term survival disease-free survival minimally invasive surgery VATS RATS |
| url | https://www.mdpi.com/2072-6694/14/11/2611 |
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