Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis

Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis

Diabetic patients are more susceptible to renal ischemia/reperfusion (I/R) injury (RI/RI) and have a poor prognosis, but the underlying mechanism remains unclear. The present study aimed to examine whether diabetes could worsen acute kidney injury induced by I/R in rats and clarify its mechanism. Co...

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Bibliographic Details
Main Authors: Dao-Jing Gong, Lei Wang, Yuan-Yuan Yang, Jian-Jian Zhang, Xiu-Heng Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Renal Failure
Subjects:
diabetes mellitus
ischemia-reperfusion
oxidative stress
inflammation
acute kidney injury
apoptosis
Online Access:http://dx.doi.org/10.1080/0886022X.2019.1643737

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