Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients

Purpose: To investigate subjective efficiency outcomes after maxillomandibular advancement (MMA) surgery in obstructive sleep apnea (OSA) patients. Material and Methods: A prospective cohort study was carried out between December 2016 and May 2021, including 30 severe or treatment-refractory OSA pat...

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Main Authors: Karel Kuik, Misha L. Tan, Jean-Pierre T. F. Ho, Jerôme A. H. Lindeboom, Jan de Lange
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/12/12/4023
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author Karel Kuik
Misha L. Tan
Jean-Pierre T. F. Ho
Jerôme A. H. Lindeboom
Jan de Lange
author_facet Karel Kuik
Misha L. Tan
Jean-Pierre T. F. Ho
Jerôme A. H. Lindeboom
Jan de Lange
author_sort Karel Kuik
collection DOAJ
description Purpose: To investigate subjective efficiency outcomes after maxillomandibular advancement (MMA) surgery in obstructive sleep apnea (OSA) patients. Material and Methods: A prospective cohort study was carried out between December 2016 and May 2021, including 30 severe or treatment-refractory OSA patients treated by MMA surgery. All patients answered four validated questionnaires: the Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ), Mandibular Function Impairment Questionnaire (MFIQ), and EQ-5D-3L (i.e., EQ-5D and EQ-VAS). They also answered one custom-made questionnaire (AMCSQ). Questionnaires were requested to be filled out 1 week before surgery and at least 6 months after surgery. Results: The total preoperative and postoperative scores on the questionnaires were compared. The mean total ESS (<i>p</i> < 0.01), FOSQ (<i>p</i> < 0.01), EQ-5D (<i>p</i> < 0.05), and EQ-VAS (<i>p</i> < 0.01) scores showed significant improvement, which was in accordance with an improvement in the mean postoperative apnea/hypopnea index score (<i>p</i> < 0.01). In contrast, the mean total MFIQ score (<i>p</i> < 0.01) indicated a decline in mandibular function. Conclusion: This study confirms the hypothesis that MMA surgery in OSA patients improves outcomes, both objectively and subjectively, with the exception of postoperative mandibular function.
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spelling doaj.art-739482b929bf444fbcd24cec581c77c12023-11-18T10:59:54ZengMDPI AGJournal of Clinical Medicine2077-03832023-06-011212402310.3390/jcm12124023Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea PatientsKarel Kuik0Misha L. Tan1Jean-Pierre T. F. Ho2Jerôme A. H. Lindeboom3Jan de Lange4Department of Oral Maxillofacial Surgery, Amsterdam University Medical Center, Location AMC, 1105 AZ Amsterdam, The NetherlandsDepartment of Oral Maxillofacial Surgery, Amsterdam University Medical Center, Location AMC, 1105 AZ Amsterdam, The NetherlandsDepartment of Oral Maxillofacial Surgery, Amsterdam University Medical Center, Location AMC, 1105 AZ Amsterdam, The NetherlandsDepartment of Oral Maxillofacial Surgery, Amsterdam University Medical Center, Location AMC, 1105 AZ Amsterdam, The NetherlandsDepartment of Oral Maxillofacial Surgery, Amsterdam University Medical Center, Location AMC, 1105 AZ Amsterdam, The NetherlandsPurpose: To investigate subjective efficiency outcomes after maxillomandibular advancement (MMA) surgery in obstructive sleep apnea (OSA) patients. Material and Methods: A prospective cohort study was carried out between December 2016 and May 2021, including 30 severe or treatment-refractory OSA patients treated by MMA surgery. All patients answered four validated questionnaires: the Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ), Mandibular Function Impairment Questionnaire (MFIQ), and EQ-5D-3L (i.e., EQ-5D and EQ-VAS). They also answered one custom-made questionnaire (AMCSQ). Questionnaires were requested to be filled out 1 week before surgery and at least 6 months after surgery. Results: The total preoperative and postoperative scores on the questionnaires were compared. The mean total ESS (<i>p</i> < 0.01), FOSQ (<i>p</i> < 0.01), EQ-5D (<i>p</i> < 0.05), and EQ-VAS (<i>p</i> < 0.01) scores showed significant improvement, which was in accordance with an improvement in the mean postoperative apnea/hypopnea index score (<i>p</i> < 0.01). In contrast, the mean total MFIQ score (<i>p</i> < 0.01) indicated a decline in mandibular function. Conclusion: This study confirms the hypothesis that MMA surgery in OSA patients improves outcomes, both objectively and subjectively, with the exception of postoperative mandibular function.https://www.mdpi.com/2077-0383/12/12/4023maxillomandibular advancementobstructive sleep apneaquality of life
spellingShingle Karel Kuik
Misha L. Tan
Jean-Pierre T. F. Ho
Jerôme A. H. Lindeboom
Jan de Lange
Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients
Journal of Clinical Medicine
maxillomandibular advancement
obstructive sleep apnea
quality of life
title Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients
title_full Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients
title_fullStr Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients
title_full_unstemmed Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients
title_short Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients
title_sort subjective efficiency evaluation after maxillomandibular advancement surgery in obstructive sleep apnea patients
topic maxillomandibular advancement
obstructive sleep apnea
quality of life
url https://www.mdpi.com/2077-0383/12/12/4023
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