Current perspectives in transplant medicine: hypothermic oxygenated perfusion
Sebastian G Michel,1 Joren C Madsen2,3 1Department of Cardiac Surgery, Ludwig-Maximilians-University, Munich, Germany; 2Department of Surgery, Center for Transplantation Sciences, 3Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA Abstract: The purpo...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2016-11-01
|
| Series: | Transplant Research and Risk Management |
| Subjects: | |
| Online Access: | https://www.dovepress.com/current-perspectives-in-transplant-medicine-hypothermic-oxygenated-per-peer-reviewed-article-TRRM |
| _version_ | 1819031019661033472 |
|---|---|
| author | Michel SG Madsen JC |
| author_facet | Michel SG Madsen JC |
| author_sort | Michel SG |
| collection | DOAJ |
| description | Sebastian G Michel,1 Joren C Madsen2,3 1Department of Cardiac Surgery, Ludwig-Maximilians-University, Munich, Germany; 2Department of Surgery, Center for Transplantation Sciences, 3Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA Abstract: The purpose of this review was to provide an update on hypothermic oxygenated perfusion as a preservation technique for whole organ allografts. Clinical and experimental data in heart, lung, liver, kidney, and pancreas/islet transplantation are summarized with a special emphasis on marginal donors and donation after circulatory death. The rationale behind hypothermic machine perfusion as well as its advantages and disadvantages compared to conventional cold storage and the competing technique, normothermic machine perfusion, are reviewed. Keywords: organ transplantation, organ preservation, hypothermic perfusion |
| first_indexed | 2024-12-21T06:39:24Z |
| format | Article |
| id | doaj.art-739683d9b1d04fdfa2c1e589794a7987 |
| institution | Directory Open Access Journal |
| issn | 1179-1616 |
| language | English |
| last_indexed | 2024-12-21T06:39:24Z |
| publishDate | 2016-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Transplant Research and Risk Management |
| spelling | doaj.art-739683d9b1d04fdfa2c1e589794a79872022-12-21T19:12:46ZengDove Medical PressTransplant Research and Risk Management1179-16162016-11-01Volume 8253029968Current perspectives in transplant medicine: hypothermic oxygenated perfusionMichel SGMadsen JCSebastian G Michel,1 Joren C Madsen2,3 1Department of Cardiac Surgery, Ludwig-Maximilians-University, Munich, Germany; 2Department of Surgery, Center for Transplantation Sciences, 3Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA Abstract: The purpose of this review was to provide an update on hypothermic oxygenated perfusion as a preservation technique for whole organ allografts. Clinical and experimental data in heart, lung, liver, kidney, and pancreas/islet transplantation are summarized with a special emphasis on marginal donors and donation after circulatory death. The rationale behind hypothermic machine perfusion as well as its advantages and disadvantages compared to conventional cold storage and the competing technique, normothermic machine perfusion, are reviewed. Keywords: organ transplantation, organ preservation, hypothermic perfusionhttps://www.dovepress.com/current-perspectives-in-transplant-medicine-hypothermic-oxygenated-per-peer-reviewed-article-TRRMOrgan preservationTransplantationHypothermiaOxygenation |
| spellingShingle | Michel SG Madsen JC Current perspectives in transplant medicine: hypothermic oxygenated perfusion Transplant Research and Risk Management Organ preservation Transplantation Hypothermia Oxygenation |
| title | Current perspectives in transplant medicine: hypothermic oxygenated perfusion |
| title_full | Current perspectives in transplant medicine: hypothermic oxygenated perfusion |
| title_fullStr | Current perspectives in transplant medicine: hypothermic oxygenated perfusion |
| title_full_unstemmed | Current perspectives in transplant medicine: hypothermic oxygenated perfusion |
| title_short | Current perspectives in transplant medicine: hypothermic oxygenated perfusion |
| title_sort | current perspectives in transplant medicine hypothermic oxygenated perfusion |
| topic | Organ preservation Transplantation Hypothermia Oxygenation |
| url | https://www.dovepress.com/current-perspectives-in-transplant-medicine-hypothermic-oxygenated-per-peer-reviewed-article-TRRM |
| work_keys_str_mv | AT michelsg currentperspectivesintransplantmedicinehypothermicoxygenatedperfusion AT madsenjc currentperspectivesintransplantmedicinehypothermicoxygenatedperfusion |