Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system
Improving the inflow characteristics of the right ventricular function and pulmonary circulatory hemodynamics was essential for more precise evaluation of newly designed heart valves. To examine a pulmonary hemodynamics, the authors have been developing a pulmonary mechanical mock circulatory system...
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| Format: | Article |
| Language: | English |
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The Japan Society of Mechanical Engineers
2016-07-01
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| Series: | Journal of Biomechanical Science and Engineering |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jbse/11/3/11_15-00356/_pdf/-char/en |
| _version_ | 1828265887785811968 |
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| author | Yusuke TSUBOKO Yasuyuki SHIRAISHI Satoshi MATSUO Akihiro YAMADA Hidekazu MIURA Takuya SHIGA Mohamed Omran HASHEM Tomoyuki YAMBE |
| author_facet | Yusuke TSUBOKO Yasuyuki SHIRAISHI Satoshi MATSUO Akihiro YAMADA Hidekazu MIURA Takuya SHIGA Mohamed Omran HASHEM Tomoyuki YAMBE |
| author_sort | Yusuke TSUBOKO |
| collection | DOAJ |
| description | Improving the inflow characteristics of the right ventricular function and pulmonary circulatory hemodynamics was essential for more precise evaluation of newly designed heart valves. To examine a pulmonary hemodynamics, the authors have been developing a pulmonary mechanical mock circulatory system. In this study, the pneumatically driven right atrium model was newly developed for clarifying the effect of atrial contraction on the dynamic behavior of pulmonary prosthetic valves. We focused on the hemodynamic behavior of the outflow mechanical heart valve of the right ventricle that could be affected by the right atrial dynamic motion. A medical-grade bileaflet valve was employed and installed into the outflow portion of the right ventricle model and examined its changes in hemodynamic behavior caused by the active right atrial contraction. With the active atrial contraction, hemodynamic waveforms of either the right ventricle or atrium were obtained using the modified pulmonary mock circulatory system. The characteristics with atrial contraction were well simulated as the natural hemodynamics. The right ventricular output increased by around 5% and the peak regurgitant flow at the moment of valve closing significantly decreased by the presence of the atrial contraction. Our mechanical circulatory system could simulate the end-diastolic right ventricular inflow characteristics. We found that the atrial contraction under the low pressure condition such as pulmonary circulation promoted earlier valve closing and prolonged closing duration of prosthetic valve. The simulation of right atrial contraction was important in the quantitative examination of right heart prosthetic valves for congenital heart malformation. |
| first_indexed | 2024-04-13T04:45:06Z |
| format | Article |
| id | doaj.art-739745b7d2214f47b5f952b9c7a93f7f |
| institution | Directory Open Access Journal |
| issn | 1880-9863 |
| language | English |
| last_indexed | 2024-04-13T04:45:06Z |
| publishDate | 2016-07-01 |
| publisher | The Japan Society of Mechanical Engineers |
| record_format | Article |
| series | Journal of Biomechanical Science and Engineering |
| spelling | doaj.art-739745b7d2214f47b5f952b9c7a93f7f2022-12-22T03:01:52ZengThe Japan Society of Mechanical EngineersJournal of Biomechanical Science and Engineering1880-98632016-07-0111315-0035615-0035610.1299/jbse.15-00356jbseEffect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory systemYusuke TSUBOKO0Yasuyuki SHIRAISHI1Satoshi MATSUO2Akihiro YAMADA3Hidekazu MIURA4Takuya SHIGA5Mohamed Omran HASHEM6Tomoyuki YAMBE7Graduate School of Biomedical Engineering, Tohoku UniversityDepartment of PreClinical Evaluation, PreClinical Research Center, Institute of Development, Aging and Cancer, Tohoku UniversityDepartment of Cardiovascular Surgery, Graduate School of Medicine, Tohoku UniversityDepartment of Medical Engineering and Cardiology, PreClinical Research Center, Institute of Development, Aging and Cancer, Tohoku UniversityDepartment of Medical Engineering and Cardiology, PreClinical Research Center, Institute of Development, Aging and Cancer, Tohoku UniversityDepartment of Medical Engineering and Cardiology, PreClinical Research Center, Institute of Development, Aging and Cancer, Tohoku UniversityDepartment of Medical Engineering and Cardiology, PreClinical Research Center, Institute of Development, Aging and Cancer, Tohoku UniversityGraduate School of Biomedical Engineering, Tohoku UniversityImproving the inflow characteristics of the right ventricular function and pulmonary circulatory hemodynamics was essential for more precise evaluation of newly designed heart valves. To examine a pulmonary hemodynamics, the authors have been developing a pulmonary mechanical mock circulatory system. In this study, the pneumatically driven right atrium model was newly developed for clarifying the effect of atrial contraction on the dynamic behavior of pulmonary prosthetic valves. We focused on the hemodynamic behavior of the outflow mechanical heart valve of the right ventricle that could be affected by the right atrial dynamic motion. A medical-grade bileaflet valve was employed and installed into the outflow portion of the right ventricle model and examined its changes in hemodynamic behavior caused by the active right atrial contraction. With the active atrial contraction, hemodynamic waveforms of either the right ventricle or atrium were obtained using the modified pulmonary mock circulatory system. The characteristics with atrial contraction were well simulated as the natural hemodynamics. The right ventricular output increased by around 5% and the peak regurgitant flow at the moment of valve closing significantly decreased by the presence of the atrial contraction. Our mechanical circulatory system could simulate the end-diastolic right ventricular inflow characteristics. We found that the atrial contraction under the low pressure condition such as pulmonary circulation promoted earlier valve closing and prolonged closing duration of prosthetic valve. The simulation of right atrial contraction was important in the quantitative examination of right heart prosthetic valves for congenital heart malformation.https://www.jstage.jst.go.jp/article/jbse/11/3/11_15-00356/_pdf/-char/enpulmonary mechanical circulatory systematrial contractionpulmonary arterial valvepneumatically driven atrium modelcongenital heart disease |
| spellingShingle | Yusuke TSUBOKO Yasuyuki SHIRAISHI Satoshi MATSUO Akihiro YAMADA Hidekazu MIURA Takuya SHIGA Mohamed Omran HASHEM Tomoyuki YAMBE Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system Journal of Biomechanical Science and Engineering pulmonary mechanical circulatory system atrial contraction pulmonary arterial valve pneumatically driven atrium model congenital heart disease |
| title | Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system |
| title_full | Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system |
| title_fullStr | Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system |
| title_full_unstemmed | Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system |
| title_short | Effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system |
| title_sort | effect of right atrial contraction on prosthetic valve function in a mechanical pulmonary circulatory system |
| topic | pulmonary mechanical circulatory system atrial contraction pulmonary arterial valve pneumatically driven atrium model congenital heart disease |
| url | https://www.jstage.jst.go.jp/article/jbse/11/3/11_15-00356/_pdf/-char/en |
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