Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis
Introduction. One of the common chronic dermatoses that have a direct impact on the quality of life of patients is acne. The occurrence of psycho-emotional disorders due to the location of elements in the open areas of the body. Given the high prevalence of acne in puberty (up to 85 % of adolescent...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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V. N. Karazin Kharkiv National University
2020-01-01
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| Series: | Фотобіологія та фотомедицина |
| Online Access: | https://periodicals.karazin.ua/photomedicine/article/view/15250/14174 |
| _version_ | 1818514527976685568 |
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| author | A.S. Radko O.K. Melekhovets T.O. Kharchenko Yu.V. Melekhovets |
| author_facet | A.S. Radko O.K. Melekhovets T.O. Kharchenko Yu.V. Melekhovets |
| author_sort | A.S. Radko |
| collection | DOAJ |
| description | Introduction. One of the common chronic dermatoses that have a direct impact on the quality of life of
patients is acne. The occurrence of psycho-emotional disorders due to the location of elements in the open areas of the body. Given the high prevalence of acne in puberty (up to 85 % of adolescents have episodes of acne of varying severity), there is a need to find new algorithms for acne treatment to prevent the progression of social
maladaptation and depressive states.
Materials and methods. The study included 140 patients who were divided into 3 groups depending
on the presence of comorbid pathology and treatment methods: group 1 — patients with acne who were
underwent standard treatment for 60 days, group 2 — patients with acne in comorbidity with demodecosis,
group 3 — patients with acne in comorbidity with demodecosis and functional disorders of the digestive system, who were additionally treated with a laser therapy. Treatment efficacy was evaluated using the GAGS scale and the DLQI questionnaire on days 14, 28 and 60 of therapy.
Results. Evaluation of the results on day 60 shows a decrease in the manifestations of inflammation by 50 %
in groups 2 and 3, and by 29 % in the standard therapy group. Improving of the quality of life in groups 2 and 3
was by 70 %, while in the group 1 — by 35 %. The following correlations were established: r = + 0.9 — between the severity of VC manifestations and the presence of comorbid pathology, r = + 0.71 — between the severity of VC and the assessment of quality of life, r = + 0.69 — between the presence of acne comorbidity with demodecosis and FDGBS and the effect on quality of life (p < 0.005).
Conclusions. Optimization of the treatment algorithm for acne patients in comorbidity with demodecosis
and functional disorders of the hepatobiliary system is achieved by the use of combined treatment using laser
therapy, which significantly improves the quality of life of patients. |
| first_indexed | 2024-12-11T00:17:03Z |
| format | Article |
| id | doaj.art-739b2b948a554113a4780f46414f166a |
| institution | Directory Open Access Journal |
| issn | 2076-0612 2523-4617 |
| language | English |
| last_indexed | 2024-12-11T00:17:03Z |
| publishDate | 2020-01-01 |
| publisher | V. N. Karazin Kharkiv National University |
| record_format | Article |
| series | Фотобіологія та фотомедицина |
| spelling | doaj.art-739b2b948a554113a4780f46414f166a2022-12-22T01:27:55ZengV. N. Karazin Kharkiv National UniversityФотобіологія та фотомедицина2076-06122523-46172020-01-012810.26565/2076-0612-2019-28-03Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosisA.S. Radko0O.K. Melekhovets1T.O. Kharchenko2Yu.V. Melekhovets3Sumy State UniversitySumy State UniversitySumy State UniversitySumy State UniversityIntroduction. One of the common chronic dermatoses that have a direct impact on the quality of life of patients is acne. The occurrence of psycho-emotional disorders due to the location of elements in the open areas of the body. Given the high prevalence of acne in puberty (up to 85 % of adolescents have episodes of acne of varying severity), there is a need to find new algorithms for acne treatment to prevent the progression of social maladaptation and depressive states. Materials and methods. The study included 140 patients who were divided into 3 groups depending on the presence of comorbid pathology and treatment methods: group 1 — patients with acne who were underwent standard treatment for 60 days, group 2 — patients with acne in comorbidity with demodecosis, group 3 — patients with acne in comorbidity with demodecosis and functional disorders of the digestive system, who were additionally treated with a laser therapy. Treatment efficacy was evaluated using the GAGS scale and the DLQI questionnaire on days 14, 28 and 60 of therapy. Results. Evaluation of the results on day 60 shows a decrease in the manifestations of inflammation by 50 % in groups 2 and 3, and by 29 % in the standard therapy group. Improving of the quality of life in groups 2 and 3 was by 70 %, while in the group 1 — by 35 %. The following correlations were established: r = + 0.9 — between the severity of VC manifestations and the presence of comorbid pathology, r = + 0.71 — between the severity of VC and the assessment of quality of life, r = + 0.69 — between the presence of acne comorbidity with demodecosis and FDGBS and the effect on quality of life (p < 0.005). Conclusions. Optimization of the treatment algorithm for acne patients in comorbidity with demodecosis and functional disorders of the hepatobiliary system is achieved by the use of combined treatment using laser therapy, which significantly improves the quality of life of patients.https://periodicals.karazin.ua/photomedicine/article/view/15250/14174 |
| spellingShingle | A.S. Radko O.K. Melekhovets T.O. Kharchenko Yu.V. Melekhovets Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis Фотобіологія та фотомедицина |
| title | Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis |
| title_full | Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis |
| title_fullStr | Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis |
| title_full_unstemmed | Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis |
| title_short | Сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis |
| title_sort | сombine therapy of patients with acne vulgaris comorbidity with functional disorder of hepatobiliary system and demodecosis |
| url | https://periodicals.karazin.ua/photomedicine/article/view/15250/14174 |
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