Liver Cirrhosis of the Viral Etiology in Children
The structure of liver cirrhosis (LC) in children of Uzbekistan was studied. 135 children with viral etiology of liver cirrhosis at the age of 7—15 years of life were examined. It was established that in the structure of viral liver cirrhosis in children, mixed etiology prevails (77.1%) with a predo...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Diagnostics and Vaccines"
2018-12-01
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| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/388 |
| _version_ | 1797881774599045120 |
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| author | F. I. Inoyatova G Z. Inogamova |
| author_facet | F. I. Inoyatova G Z. Inogamova |
| author_sort | F. I. Inoyatova |
| collection | DOAJ |
| description | The structure of liver cirrhosis (LC) in children of Uzbekistan was studied. 135 children with viral etiology of liver cirrhosis at the age of 7—15 years of life were examined. It was established that in the structure of viral liver cirrhosis in children, mixed etiology prevails (77.1%) with a predominance of HDV infection (B + C + D — 35.6% and B + D — 23.7%). Mixed infection is considered as a predictor of disease progression, especially in cases of overlap of HDV infection, which was also expressed by the frequent identification of the decompensated stage of the liver cirrhosis C-class of Child-Pugh and complications. Levels of N-terminal propeptides and C-terminal telopeptides of type I collagen in children with liver cirrhosis can serve as markers of compensation and progression of the disease. |
| first_indexed | 2024-04-10T03:25:31Z |
| format | Article |
| id | doaj.art-739f6d0841af4e80a2a8d06a8c7479e3 |
| institution | Directory Open Access Journal |
| issn | 2072-8107 |
| language | Russian |
| last_indexed | 2024-04-10T03:25:31Z |
| publishDate | 2018-12-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj.art-739f6d0841af4e80a2a8d06a8c7479e32023-03-13T07:28:25ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072018-12-01174293310.22627/2072-8107-2018-17-4-29-33363Liver Cirrhosis of the Viral Etiology in ChildrenF. I. Inoyatova0G Z. Inogamova1Республиканский специализированный научно-практический медицинский центр Педиатрии МЗ РУзРеспубликанский специализированный научно-практический медицинский центр Педиатрии МЗ РУзThe structure of liver cirrhosis (LC) in children of Uzbekistan was studied. 135 children with viral etiology of liver cirrhosis at the age of 7—15 years of life were examined. It was established that in the structure of viral liver cirrhosis in children, mixed etiology prevails (77.1%) with a predominance of HDV infection (B + C + D — 35.6% and B + D — 23.7%). Mixed infection is considered as a predictor of disease progression, especially in cases of overlap of HDV infection, which was also expressed by the frequent identification of the decompensated stage of the liver cirrhosis C-class of Child-Pugh and complications. Levels of N-terminal propeptides and C-terminal telopeptides of type I collagen in children with liver cirrhosis can serve as markers of compensation and progression of the disease.https://detinf.elpub.ru/jour/article/view/388цирроз печениэтиологияhdv-инфекциядети |
| spellingShingle | F. I. Inoyatova G Z. Inogamova Liver Cirrhosis of the Viral Etiology in Children Детские инфекции (Москва) цирроз печени этиология hdv-инфекция дети |
| title | Liver Cirrhosis of the Viral Etiology in Children |
| title_full | Liver Cirrhosis of the Viral Etiology in Children |
| title_fullStr | Liver Cirrhosis of the Viral Etiology in Children |
| title_full_unstemmed | Liver Cirrhosis of the Viral Etiology in Children |
| title_short | Liver Cirrhosis of the Viral Etiology in Children |
| title_sort | liver cirrhosis of the viral etiology in children |
| topic | цирроз печени этиология hdv-инфекция дети |
| url | https://detinf.elpub.ru/jour/article/view/388 |
| work_keys_str_mv | AT fiinoyatova livercirrhosisoftheviraletiologyinchildren AT gzinogamova livercirrhosisoftheviraletiologyinchildren |