Early Hyperdynamic Sepsis Alters Coronary Blood Flow Regulation in Porcine Fecal Peritonitis

Early Hyperdynamic Sepsis Alters Coronary Blood Flow Regulation in Porcine Fecal Peritonitis

Background: Sepsis is a common condition known to impair blood flow regulation and microcirculation, which can ultimately lead to organ dysfunction but such contribution of the coronary circulation remains to be clarified. We investigated coronary blood flow regulatory mechanisms, including autoregu...

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Main Authors: Céline Boudart, Fuhong Su, Lorenzo Pitisci, Arnaud Dhoine, Olivier Duranteau, Pascale Jespers, Antoine Herpain, Rebecca Vanderpool, Serge Brimioulle, Jacques Creteur, Robert Naeije, Luc Van Obbergh, Laurence Dewachter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Physiology
Subjects:
coronary blood flow
autoregulation
sepsis
metabolic regulation
endothelial function
microcirculation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.754570/full

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