Knockdown of EIF4G1 in NSCLC induces CXCL8 secretion

Knockdown of EIF4G1 in NSCLC induces CXCL8 secretion

Non-small cell lung cancer (NSCLC) is the most common type of lung tumor; however, we lack effective early detection indicators and therapeutic targets. Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) is vital to initiate protein synthesis, acting as a scaffolding protein for the eukaryo...

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Bibliographic Details
Main Authors: Ziyang He, Fangyi Li, Xinyi Zhang, Dacheng Gao, Zhiwen Zhang, Rui Xu, Xingguo Cao, Qiyuan Shan, Zhen Ren, Yali Liu, Zengguang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
NSCLC
EIF4G1
CXCL8
IL8
chemotaxis
MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1346383/full

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