Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine
Background: Postoperative shivering is very common and followed by many problems such as increasing oxygen consumption, blood pressure, intracranial and intraocular pressure, and postoperative pain. Therefore, prevention of shivering is important, especially in elderly and ischemic heart disease pat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | International Journal of Preventive Medicine |
| Subjects: | |
| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2013;volume=4;issue=7;spage=818;epage=824;aulast=Entezariasl |
| _version_ | 1818933852754673664 |
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| author | Masood Entezariasl Khatereh Isazadehfar |
| author_facet | Masood Entezariasl Khatereh Isazadehfar |
| author_sort | Masood Entezariasl |
| collection | DOAJ |
| description | Background: Postoperative shivering is very common and followed by many problems such as increasing oxygen consumption, blood pressure, intracranial and intraocular pressure, and postoperative pain. Therefore, prevention of shivering is important, especially in elderly and ischemic heart disease patients. The goal of this study was to compare the effect of pethidine (meperidine), dexamethasone, and placebo on prevention of shivering.
Methods: This double-blind clinical trial study was carried out on 120 patients who were candidates for surgery under general anesthesia. The patients were randomly divided into three groups. Induction and maintenance of anesthesia for all patients were similar. Temperature of patients was measured every 5 min interval. After induction, saline 0.9%, dexamethasone and pethidine were injected to groups a, b, and c, respectively. In recovery, patients were controlled for visible shivering. All data were statistically analyzed by analysis of variance (ANOVA) and Chi-square tests.
Results: There were no significant differences among three mentioned groups regarding gender, age, duration of surgery and anesthesia, extubation time, duration of recovery, and basic clinical characteristics. Nineteen cases (47.5%) of placebo group had postoperative shivering, whereas in dexamethasone group only four cases (10%) had shivering and the difference between the two groups was significant. Also in pethidine group, 15 cases (37.5%) had shivering and the difference with placebo group was significant (P value = 0.001).
Conclusion: The present study showed that pethidine and dexamethasone are effective drugs for prevention of postoperative shivering in elective surgery and the effect of dexamethasone in preventing the postoperative shivering is better than pethidine. |
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| format | Article |
| id | doaj.art-73a6026cfe594b87b25c6ae3a457dced |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-20T04:54:58Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-73a6026cfe594b87b25c6ae3a457dced2022-12-21T19:52:43ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132013-01-0147818824Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidineMasood EntezariaslKhatereh IsazadehfarBackground: Postoperative shivering is very common and followed by many problems such as increasing oxygen consumption, blood pressure, intracranial and intraocular pressure, and postoperative pain. Therefore, prevention of shivering is important, especially in elderly and ischemic heart disease patients. The goal of this study was to compare the effect of pethidine (meperidine), dexamethasone, and placebo on prevention of shivering. Methods: This double-blind clinical trial study was carried out on 120 patients who were candidates for surgery under general anesthesia. The patients were randomly divided into three groups. Induction and maintenance of anesthesia for all patients were similar. Temperature of patients was measured every 5 min interval. After induction, saline 0.9%, dexamethasone and pethidine were injected to groups a, b, and c, respectively. In recovery, patients were controlled for visible shivering. All data were statistically analyzed by analysis of variance (ANOVA) and Chi-square tests. Results: There were no significant differences among three mentioned groups regarding gender, age, duration of surgery and anesthesia, extubation time, duration of recovery, and basic clinical characteristics. Nineteen cases (47.5%) of placebo group had postoperative shivering, whereas in dexamethasone group only four cases (10%) had shivering and the difference between the two groups was significant. Also in pethidine group, 15 cases (37.5%) had shivering and the difference with placebo group was significant (P value = 0.001). Conclusion: The present study showed that pethidine and dexamethasone are effective drugs for prevention of postoperative shivering in elective surgery and the effect of dexamethasone in preventing the postoperative shivering is better than pethidine.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2013;volume=4;issue=7;spage=818;epage=824;aulast=EntezariaslDexamethasonegeneral anesthesiashiveringsurgerypethidine |
| spellingShingle | Masood Entezariasl Khatereh Isazadehfar Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine International Journal of Preventive Medicine Dexamethasone general anesthesia shivering surgery pethidine |
| title | Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine |
| title_full | Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine |
| title_fullStr | Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine |
| title_full_unstemmed | Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine |
| title_short | Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine |
| title_sort | dexamethasone for prevention of postoperative shivering a randomized double blind comparison with pethidine |
| topic | Dexamethasone general anesthesia shivering surgery pethidine |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2013;volume=4;issue=7;spage=818;epage=824;aulast=Entezariasl |
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