Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review
Lifestyle strategies are considered first-line treatment for the management of polycystic ovary syndrome (PCOS). However, complementary therapies, including nutrient supplementation, have been identified as a potential adjunct therapy. Therefore, we systematically mapped the available literature to...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-12-01
|
| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/11/12/3349 |
| _version_ | 1797381869502726144 |
|---|---|
| author | Nicole Scannell Evangeline Mantzioris Vibhuti Rao Chhiti Pandey Carolyn Ee Aya Mousa Lisa Moran Anthony Villani |
| author_facet | Nicole Scannell Evangeline Mantzioris Vibhuti Rao Chhiti Pandey Carolyn Ee Aya Mousa Lisa Moran Anthony Villani |
| author_sort | Nicole Scannell |
| collection | DOAJ |
| description | Lifestyle strategies are considered first-line treatment for the management of polycystic ovary syndrome (PCOS). However, complementary therapies, including nutrient supplementation, have been identified as a potential adjunct therapy. Therefore, we systematically mapped the available literature to identify the type and frequency of the use of nutraceutical and micronutrient supplementation for the management of PCOS features. A systematic search of the literature was conducted using CINAHL, Cochrane reviews, Medline, PsycINFO, Scopus and LILACS. All types of study designs were included if they reported on the use of nutraceuticals and/or micronutrient supplementation on features of PCOS in women aged ≥18 years. A total of 344 articles were included. Forty-one supplements were identified, with the most frequently investigated being inositols (n = 86), vitamin D (n = 53), N-acetylcysteine (n = 27) and omega-3 fatty acids (n = 25). Reproductive outcomes were the most commonly reported (n = 285; 83%), followed by metabolic (n = 229; 67%), anthropometric (n = 197; 57%) and psychological (n = 8; 2%). Our results identified that nutraceutical and micronutrient supplementation require further investigation of psychological outcomes in women with PCOS. Moreover, adequately powered primary studies are warranted to investigate therapeutic doses needed for clinical benefits. |
| first_indexed | 2024-03-08T20:57:44Z |
| format | Article |
| id | doaj.art-73a81abd0d9742d487e00d6395dee29f |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-08T20:57:44Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-73a81abd0d9742d487e00d6395dee29f2023-12-22T13:55:23ZengMDPI AGBiomedicines2227-90592023-12-011112334910.3390/biomedicines11123349Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping ReviewNicole Scannell0Evangeline Mantzioris1Vibhuti Rao2Chhiti Pandey3Carolyn Ee4Aya Mousa5Lisa Moran6Anthony Villani7School of Health, University of the Sunshine Coast, Sunshine Coast, QLD 4556, AustraliaUniSA Clinical & Health Sciences, Alliance for Research in Exercise, Nutrition, and Activity (ARENA), University of South Australia, Adelaide, SA 5000, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2145, AustraliaMonash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3800, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2145, AustraliaMonash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3800, AustraliaMonash Centre for Health Research and Implementation (MCHRI), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3800, AustraliaSchool of Health, University of the Sunshine Coast, Sunshine Coast, QLD 4556, AustraliaLifestyle strategies are considered first-line treatment for the management of polycystic ovary syndrome (PCOS). However, complementary therapies, including nutrient supplementation, have been identified as a potential adjunct therapy. Therefore, we systematically mapped the available literature to identify the type and frequency of the use of nutraceutical and micronutrient supplementation for the management of PCOS features. A systematic search of the literature was conducted using CINAHL, Cochrane reviews, Medline, PsycINFO, Scopus and LILACS. All types of study designs were included if they reported on the use of nutraceuticals and/or micronutrient supplementation on features of PCOS in women aged ≥18 years. A total of 344 articles were included. Forty-one supplements were identified, with the most frequently investigated being inositols (n = 86), vitamin D (n = 53), N-acetylcysteine (n = 27) and omega-3 fatty acids (n = 25). Reproductive outcomes were the most commonly reported (n = 285; 83%), followed by metabolic (n = 229; 67%), anthropometric (n = 197; 57%) and psychological (n = 8; 2%). Our results identified that nutraceutical and micronutrient supplementation require further investigation of psychological outcomes in women with PCOS. Moreover, adequately powered primary studies are warranted to investigate therapeutic doses needed for clinical benefits.https://www.mdpi.com/2227-9059/11/12/3349nutraceuticalsmicronutrientspolycystic ovary syndromepcossupplements |
| spellingShingle | Nicole Scannell Evangeline Mantzioris Vibhuti Rao Chhiti Pandey Carolyn Ee Aya Mousa Lisa Moran Anthony Villani Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review Biomedicines nutraceuticals micronutrients polycystic ovary syndrome pcos supplements |
| title | Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review |
| title_full | Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review |
| title_fullStr | Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review |
| title_full_unstemmed | Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review |
| title_short | Type and Frequency in Use of Nutraceutical and Micronutrient Supplementation for the Management of Polycystic Ovary Syndrome: A Systematic Scoping Review |
| title_sort | type and frequency in use of nutraceutical and micronutrient supplementation for the management of polycystic ovary syndrome a systematic scoping review |
| topic | nutraceuticals micronutrients polycystic ovary syndrome pcos supplements |
| url | https://www.mdpi.com/2227-9059/11/12/3349 |
| work_keys_str_mv | AT nicolescannell typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT evangelinemantzioris typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT vibhutirao typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT chhitipandey typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT carolynee typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT ayamousa typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT lisamoran typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview AT anthonyvillani typeandfrequencyinuseofnutraceuticalandmicronutrientsupplementationforthemanagementofpolycysticovarysyndromeasystematicscopingreview |