BAK regulates catalase release from peroxisomes

BAK regulates catalase release from peroxisomes

Loss of voltage-dependent anion channel 2 (VDAC2) leads to impaired peroxisome biogenesis in mammalian cells. Knockdown of BAK restores peroxisomal biogenesis in VDAC2-deficient cells, where BAK localization shifts from mitochondria to peroxisomes. Moreover, overexpression of BAK activators in wild-...

Full description

Bibliographic Details
Main Authors: Yukio Fujiki, Non Miyata, Satoru Mukai, Kanji Okumoto, Emily H. Cheng
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Molecular & Cellular Oncology
Subjects:
apoptosis
bak
catalase
cho mutant
membrane permeabilization
oligomerization
oxidative stress
peroxisome
reactive oxygen species
vdac2
Online Access:http://dx.doi.org/10.1080/23723556.2017.1306610

Similar Items

Similar Items