Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report
Sihao Shen,1 Jiangfeng Feng,1 Xiuzu Song,2 Wenzhong Xiang2 1Department of Dermatology, Hangzhou Third People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Dermatology, Hangzhou Third People’s Hospital, Affiliated Hangzhou Dermatology Hospital,...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2023-07-01
|
| Series: | Clinical, Cosmetic and Investigational Dermatology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/reflectance-confocal-microscopy-of-adult-periorificial-dermatitis-a-ca-peer-reviewed-fulltext-article-CCID |
| _version_ | 1827897376083279872 |
|---|---|
| author | Shen S Feng J Song X Xiang W |
| author_facet | Shen S Feng J Song X Xiang W |
| author_sort | Shen S |
| collection | DOAJ |
| description | Sihao Shen,1 Jiangfeng Feng,1 Xiuzu Song,2 Wenzhong Xiang2 1Department of Dermatology, Hangzhou Third People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Dermatology, Hangzhou Third People’s Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Wenzhong Xiang, Department of Dermatology, Hangzhou Third People’s Hospital; Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, Westlake Ave 38, Hangzhou, 310009, People’s Republic of China, Tel +86 13588004268, Email xiangwenzhong@126.comAbstract: Periorificial dermatitis (PD) is an inflammatory disorder of the facial skin that mainly occurs around the mouth and manifests as erythema, papules, pustules, scales and other lesions. Special attention is needed in the clinical diagnosis of PD to distinguish it from acne, seborrheic dermatitis (SD), granulomatous rosacea (GR), sarcoidosis and childhood granulomatous periorificial dermatitis (CGPD). We used reflectance confocal microscopy (RCM) images of a patient with PD to assist in the diagnosis of PD. RCM of PD showed slight oedema of the spinous layer. Numerous dendritic cells, scattered hair follicular keratotic plugging and hair follicle dilatation were observed. The dilation and congestion of superficial dermis blood vessels, an increasing vascular density and accelerated blood flow, and a greater abundance of infiltrated inflammatory cells were also detected.Keywords: periorificial dermatitis, reflectance confocal microscopy, acne, seborrheic dermatitis, granulomatous rosacea, sarcoidosis, childhood granulomatous periorificial dermatitis |
| first_indexed | 2024-03-12T22:48:14Z |
| format | Article |
| id | doaj.art-73a986de2df940f289859d8ba2f4efc7 |
| institution | Directory Open Access Journal |
| issn | 1178-7015 |
| language | English |
| last_indexed | 2024-03-12T22:48:14Z |
| publishDate | 2023-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj.art-73a986de2df940f289859d8ba2f4efc72023-07-20T19:06:35ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152023-07-01Volume 161865186985306Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case ReportShen SFeng JSong XXiang WSihao Shen,1 Jiangfeng Feng,1 Xiuzu Song,2 Wenzhong Xiang2 1Department of Dermatology, Hangzhou Third People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Dermatology, Hangzhou Third People’s Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Wenzhong Xiang, Department of Dermatology, Hangzhou Third People’s Hospital; Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, Westlake Ave 38, Hangzhou, 310009, People’s Republic of China, Tel +86 13588004268, Email xiangwenzhong@126.comAbstract: Periorificial dermatitis (PD) is an inflammatory disorder of the facial skin that mainly occurs around the mouth and manifests as erythema, papules, pustules, scales and other lesions. Special attention is needed in the clinical diagnosis of PD to distinguish it from acne, seborrheic dermatitis (SD), granulomatous rosacea (GR), sarcoidosis and childhood granulomatous periorificial dermatitis (CGPD). We used reflectance confocal microscopy (RCM) images of a patient with PD to assist in the diagnosis of PD. RCM of PD showed slight oedema of the spinous layer. Numerous dendritic cells, scattered hair follicular keratotic plugging and hair follicle dilatation were observed. The dilation and congestion of superficial dermis blood vessels, an increasing vascular density and accelerated blood flow, and a greater abundance of infiltrated inflammatory cells were also detected.Keywords: periorificial dermatitis, reflectance confocal microscopy, acne, seborrheic dermatitis, granulomatous rosacea, sarcoidosis, childhood granulomatous periorificial dermatitishttps://www.dovepress.com/reflectance-confocal-microscopy-of-adult-periorificial-dermatitis-a-ca-peer-reviewed-fulltext-article-CCIDperiorificial dermatitisreflectance confocal microscopyacneseborrheic dermatitisgranulomatous rosaceasarcoidosischildhood granulomatous periorificial dermatitis |
| spellingShingle | Shen S Feng J Song X Xiang W Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report Clinical, Cosmetic and Investigational Dermatology periorificial dermatitis reflectance confocal microscopy acne seborrheic dermatitis granulomatous rosacea sarcoidosis childhood granulomatous periorificial dermatitis |
| title | Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report |
| title_full | Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report |
| title_fullStr | Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report |
| title_full_unstemmed | Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report |
| title_short | Reflectance Confocal Microscopy of Adult Periorificial Dermatitis: A Case Report |
| title_sort | reflectance confocal microscopy of adult periorificial dermatitis a case report |
| topic | periorificial dermatitis reflectance confocal microscopy acne seborrheic dermatitis granulomatous rosacea sarcoidosis childhood granulomatous periorificial dermatitis |
| url | https://www.dovepress.com/reflectance-confocal-microscopy-of-adult-periorificial-dermatitis-a-ca-peer-reviewed-fulltext-article-CCID |
| work_keys_str_mv | AT shens reflectanceconfocalmicroscopyofadultperiorificialdermatitisacasereport AT fengj reflectanceconfocalmicroscopyofadultperiorificialdermatitisacasereport AT songx reflectanceconfocalmicroscopyofadultperiorificialdermatitisacasereport AT xiangw reflectanceconfocalmicroscopyofadultperiorificialdermatitisacasereport |