Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film
The electrochemical reduction of nitric oxide (NO) catalyzed by metal porphyrins as enzyme mimics provides a promising way to understand its roles in biological denitrification. Here, a stepwise electrocatalytic reduction of NO was demonstrated by a cationic picket-fence porphyrin incorporated in an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-03-01
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| Series: | Electrochemistry Communications |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1388248119300281 |
| _version_ | 1811287495828045824 |
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| author | Xianjiu Liao Lei Zhang Sina Wang Jianping Lei |
| author_facet | Xianjiu Liao Lei Zhang Sina Wang Jianping Lei |
| author_sort | Xianjiu Liao |
| collection | DOAJ |
| description | The electrochemical reduction of nitric oxide (NO) catalyzed by metal porphyrins as enzyme mimics provides a promising way to understand its roles in biological denitrification. Here, a stepwise electrocatalytic reduction of NO was demonstrated by a cationic picket-fence porphyrin incorporated in an ultrathin phospholipid film. The mass transport-corrected Tafel slopes demonstrated −117 mV/dec and −60 mV/dec for the first and second reduction of NO at physiological pH (pH 7.0), respectively, suggesting a distinguish mechanism for the two-step reduction of NO. More significantly, the potential of the first reduction is constant at −0.37 V vs. NHE while the second potential shifted positively with decreasing pH, giving pH dependence with a slope of −43 mV/pH. A kinetic mechanism of electrocatalytic NO reduction is thus proposed, and provides a promising hint for decoding the functions of the various enzymes. Keywords: Iron porphyrin, Electrocatalysis, Nitric oxide, Kinetic mechanism, Phospholipid |
| first_indexed | 2024-04-13T03:19:40Z |
| format | Article |
| id | doaj.art-73aa25a3be554558bcbfd2b560dc7e6e |
| institution | Directory Open Access Journal |
| issn | 1388-2481 |
| language | English |
| last_indexed | 2024-04-13T03:19:40Z |
| publishDate | 2019-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Electrochemistry Communications |
| spelling | doaj.art-73aa25a3be554558bcbfd2b560dc7e6e2022-12-22T03:04:49ZengElsevierElectrochemistry Communications1388-24812019-03-011006063Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid filmXianjiu Liao0Lei Zhang1Sina Wang2Jianping Lei3School of Pharmacy, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China; State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, ChinaState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, ChinaState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, ChinaState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China; Corresponding author.The electrochemical reduction of nitric oxide (NO) catalyzed by metal porphyrins as enzyme mimics provides a promising way to understand its roles in biological denitrification. Here, a stepwise electrocatalytic reduction of NO was demonstrated by a cationic picket-fence porphyrin incorporated in an ultrathin phospholipid film. The mass transport-corrected Tafel slopes demonstrated −117 mV/dec and −60 mV/dec for the first and second reduction of NO at physiological pH (pH 7.0), respectively, suggesting a distinguish mechanism for the two-step reduction of NO. More significantly, the potential of the first reduction is constant at −0.37 V vs. NHE while the second potential shifted positively with decreasing pH, giving pH dependence with a slope of −43 mV/pH. A kinetic mechanism of electrocatalytic NO reduction is thus proposed, and provides a promising hint for decoding the functions of the various enzymes. Keywords: Iron porphyrin, Electrocatalysis, Nitric oxide, Kinetic mechanism, Phospholipidhttp://www.sciencedirect.com/science/article/pii/S1388248119300281 |
| spellingShingle | Xianjiu Liao Lei Zhang Sina Wang Jianping Lei Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film Electrochemistry Communications |
| title | Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film |
| title_full | Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film |
| title_fullStr | Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film |
| title_full_unstemmed | Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film |
| title_short | Stepwise electrocatalytic reduction of nitric oxide by cationic picket-fence porphyrin in an ultrathin phospholipid film |
| title_sort | stepwise electrocatalytic reduction of nitric oxide by cationic picket fence porphyrin in an ultrathin phospholipid film |
| url | http://www.sciencedirect.com/science/article/pii/S1388248119300281 |
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