A case of gingival stem cell administration using adipose tissue-derived stem cells
Adipose tissue-derived stem cells (ASCs) are reported to be capable of differentiating into all of mature cells, including bones and cartilage as same as bone marrow mesenchymal stem cells. In this study, we examined to treat periodontal disease using autologous ASCs to avoid rejection by transplant...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Oral Research and Review |
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| Online Access: | http://www.jorr.org/article.asp?issn=2249-4987;year=2020;volume=12;issue=1;spage=42;epage=46;aulast=Suzuki |
| _version_ | 1818444008350810112 |
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| author | Yukako Suzuki |
| author_facet | Yukako Suzuki |
| author_sort | Yukako Suzuki |
| collection | DOAJ |
| description | Adipose tissue-derived stem cells (ASCs) are reported to be capable of differentiating into all of mature cells, including bones and cartilage as same as bone marrow mesenchymal stem cells. In this study, we examined to treat periodontal disease using autologous ASCs to avoid rejection by transplantation. After autologous ASCs were injected into the gingiva, X-ray examination, periodontal pocket examination, and bleeding on probing were good results, and we obtained regeneration of periodontal tissue. Autologous ASCs are also easy to collect. Compared with other periodontal regeneration treatments, the burden on patients with less risk of postoperative infection is also less. In future, we hope to consider combined use with growth factors to aim at the alveolar bone and periodontal tissues regeneration. Moreover, we hope to conduct further investigations with a large number of cases over a long period of time. |
| first_indexed | 2024-12-14T19:09:06Z |
| format | Article |
| id | doaj.art-73ab3d8d9d5c4b5db7c5a2a54146dd5a |
| institution | Directory Open Access Journal |
| issn | 2249-4987 2394-2541 |
| language | English |
| last_indexed | 2024-12-14T19:09:06Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Oral Research and Review |
| spelling | doaj.art-73ab3d8d9d5c4b5db7c5a2a54146dd5a2022-12-21T22:50:46ZengWolters Kluwer Medknow PublicationsJournal of Oral Research and Review2249-49872394-25412020-01-01121424610.4103/jorr.jorr_35_19A case of gingival stem cell administration using adipose tissue-derived stem cellsYukako SuzukiAdipose tissue-derived stem cells (ASCs) are reported to be capable of differentiating into all of mature cells, including bones and cartilage as same as bone marrow mesenchymal stem cells. In this study, we examined to treat periodontal disease using autologous ASCs to avoid rejection by transplantation. After autologous ASCs were injected into the gingiva, X-ray examination, periodontal pocket examination, and bleeding on probing were good results, and we obtained regeneration of periodontal tissue. Autologous ASCs are also easy to collect. Compared with other periodontal regeneration treatments, the burden on patients with less risk of postoperative infection is also less. In future, we hope to consider combined use with growth factors to aim at the alveolar bone and periodontal tissues regeneration. Moreover, we hope to conduct further investigations with a large number of cases over a long period of time.http://www.jorr.org/article.asp?issn=2249-4987;year=2020;volume=12;issue=1;spage=42;epage=46;aulast=Suzukiadipose tissue-derived stem cellsperiodontal diseaseperiodontal tissue regeneration |
| spellingShingle | Yukako Suzuki A case of gingival stem cell administration using adipose tissue-derived stem cells Journal of Oral Research and Review adipose tissue-derived stem cells periodontal disease periodontal tissue regeneration |
| title | A case of gingival stem cell administration using adipose tissue-derived stem cells |
| title_full | A case of gingival stem cell administration using adipose tissue-derived stem cells |
| title_fullStr | A case of gingival stem cell administration using adipose tissue-derived stem cells |
| title_full_unstemmed | A case of gingival stem cell administration using adipose tissue-derived stem cells |
| title_short | A case of gingival stem cell administration using adipose tissue-derived stem cells |
| title_sort | case of gingival stem cell administration using adipose tissue derived stem cells |
| topic | adipose tissue-derived stem cells periodontal disease periodontal tissue regeneration |
| url | http://www.jorr.org/article.asp?issn=2249-4987;year=2020;volume=12;issue=1;spage=42;epage=46;aulast=Suzuki |
| work_keys_str_mv | AT yukakosuzuki acaseofgingivalstemcelladministrationusingadiposetissuederivedstemcells AT yukakosuzuki caseofgingivalstemcelladministrationusingadiposetissuederivedstemcells |